A simple marker might predict which teeth can be saved without root canal

NCT ID NCT06960603

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study tests whether the level of a specific inflammatory marker (MMP9) in the dental pulp can predict the success of a full pulpotomy, a procedure that removes the inflamed pulp from the crown of a tooth and seals it with a special material. Adults with deep cavities causing pulpitis in a molar will undergo the procedure, and their pain and healing will be tracked for up to two years. The goal is to see if measuring this marker during treatment can help identify which teeth are likely to heal successfully, potentially offering a less invasive alternative to root canal therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Full pulpotomy procedure with calcium silicate capping material
What this could lead to
If successful, this could help dentists predict which teeth will respond well to a less invasive root canal alternative, potentially saving more natural teeth.
What could go wrong
This is a small, early-stage study. The marker may not reliably predict outcomes, and the procedure itself carries risks like infection or treatment failure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jordan university of science and Technology

    Irbid, Irbid Governorate, 22110, Jordan