New dental cements could save painful teeth from root canals

NCT ID NCT06802536

Ongoing Disease control Sponsor: Firat University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests two calcium silicate-based dental cements, Biodentine and NeoPutty, for treating irreversible pulpitis (severe tooth nerve inflammation) in adults. Sixty participants with deep cavities and spontaneous pain will receive a single-session pulpotomy, where the inflamed pulp is removed and covered with one of the materials. The goal is to see if the tooth survives without needing a root canal, with follow-ups at 3, 6, and 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Biodentine and NeoPutty (calcium silicate-based dental cements)
What this could lead to: If successful, this could offer a simpler, tooth-saving alternative to root canal treatment for inflamed dental pulp.
What could go wrong: This is a small, early-phase trial with only 60 participants. The treatments may fail to relieve pain, requiring root canal therapy instead.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PULPITIS - IRREVERSIBLE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULPITIS - IRREVERSIBLE

Contacts and locations

Locations

Firat University

Elâzığ, 23119, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.