New dental cements could save painful teeth from root canals

NCT ID NCT06802536

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests two calcium silicate-based dental cements, Biodentine and NeoPutty, for treating irreversible pulpitis (severe tooth nerve inflammation) in adults. Sixty participants with deep cavities and spontaneous pain will receive a single-session pulpotomy, where the inflamed pulp is removed and covered with one of the materials. The goal is to see if the tooth survives without needing a root canal, with follow-ups at 3, 6, and 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Biodentine and NeoPutty (calcium silicate-based dental cements)

What this could lead to

If successful, this could offer a simpler, tooth-saving alternative to root canal treatment for inflamed dental pulp.

What could go wrong

This is a small, early-phase trial with only 60 participants. The treatments may fail to relieve pain, requiring root canal therapy instead.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Firat University

    Elâzığ, 23119, Turkey (Türkiye)