Vitamin d may soothe root canal pain, small trial hints
NCT ID NCT07579637
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking vitamin D3 before a root canal can reduce pain afterward. Fifty-four adults with low vitamin D and painful tooth inflammation will receive either a single high dose, a three-day course, or a placebo. Pain levels and painkiller use will be tracked for 48 hours after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vitamin D3 (cholecalciferol) oral capsules
What this could lead to
If it works, this could offer a simple, low-cost way to manage dental pain after root canals, especially for people with low vitamin D.
What could go wrong
This is a small, early-stage trial with only 54 participants, so results may not apply widely. The effect on pain may be modest or no better than placebo.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Future University in Egypt
New Cairo, Select A State Or Province, Egypt