Vitamin d may soothe root canal pain, small trial hints
NCT ID NCT07579637
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking vitamin D3 before a root canal can reduce pain afterward. Fifty-four adults with low vitamin D and painful tooth inflammation will receive either a single high dose, a three-day course, or a placebo. Pain levels and painkiller use will be tracked for 48 hours after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Vitamin D3 (cholecalciferol) oral capsules
- What this could lead to
- If it works, this could offer a simple, low-cost way to manage dental pain after root canals, especially for people with low vitamin D.
- What could go wrong
- This is a small, early-stage trial with only 54 participants, so results may not apply widely. The effect on pain may be modest or no better than placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Future University in Egypt
New Cairo, Select A State Or Province, Egypt
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