New antibiotic paste could replace root canals in Kids' teeth

NCT ID NCT06811636

First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study compares two treatments for infected baby molars in children aged 3 to 8: a less invasive method using a triple antibiotic paste versus a standard root canal with a calcium hydroxide-iodoform paste. The goal is to see which approach better relieves pain, swelling, and infection signs over time. Researchers will check both clinical symptoms and X-ray results to determine success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
triple antibiotic paste and calcium hydroxide-iodoform paste
What this could lead to
If successful, this could offer a simpler, less invasive option for treating infected baby teeth in children, potentially avoiding the need for full root canals.
What could go wrong
This is a small, early-stage study with only 74 children, so results may not apply to everyone. The antibiotic paste might not fully clear the infection, and there is a risk of allergic reactions or tooth damage.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Canakkale Onsekiz Mart University

    Çanakkale, Kepez, 17100, Turkey (Türkiye)

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