Root canal bacteria under the microscope: new study aims to improve treatment

NCT ID NCT07637305

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looked at bacteria in root canal infections, comparing painful and painless cases. Researchers used DNA testing to identify bacteria before and after cleaning with two different strengths of sodium hypochlorite. The goal was to see how well the cleaning removes bacteria and which types are present in each case.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sodium hypochlorite irrigation with ultrasonic activation

What this could lead to

If successful, this could help dentists choose better treatments for root canal infections by understanding which bacteria are present.

What could go wrong

This is a very small pilot study with only 24 participants, so results may not apply to everyone. It only looks at bacteria, not long-term healing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental abscess dental pulp disorder periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dental and Oral Hospital of Hasanuddin University

    Makassar, South Sulawesi, 90245, Indonesia