Root canal bacteria under the microscope: new study aims to improve treatment

NCT ID NCT07637305

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study looked at bacteria in root canal infections, comparing painful and painless cases. Researchers used DNA testing to identify bacteria before and after cleaning with two different strengths of sodium hypochlorite. The goal was to see how well the cleaning removes bacteria and which types are present in each case.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
sodium hypochlorite irrigation with ultrasonic activation
What this could lead to
If successful, this could help dentists choose better treatments for root canal infections by understanding which bacteria are present.
What could go wrong
This is a very small pilot study with only 24 participants, so results may not apply to everyone. It only looks at bacteria, not long-term healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dental and Oral Hospital of Hasanuddin University

    Makassar, South Sulawesi, 90245, Indonesia

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Other studies related to the condition(s) this trial covers.