Root canal bacteria under the microscope: new study aims to improve treatment
NCT ID NCT07637305
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This pilot study looked at bacteria in root canal infections, comparing painful and painless cases. Researchers used DNA testing to identify bacteria before and after cleaning with two different strengths of sodium hypochlorite. The goal was to see how well the cleaning removes bacteria and which types are present in each case.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- sodium hypochlorite irrigation with ultrasonic activation
- What this could lead to
- If successful, this could help dentists choose better treatments for root canal infections by understanding which bacteria are present.
- What could go wrong
- This is a very small pilot study with only 24 participants, so results may not apply to everyone. It only looks at bacteria, not long-term healing.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dental and Oral Hospital of Hasanuddin University
Makassar, South Sulawesi, 90245, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gentler root canal tool ease post-treatment pain?
- Root canal battle: which medicament kills more bacteria?
- Laser vs ultrasound: which cleans root canals better?
- Scientists track germs in root canals during standard dental care
- New nanozyme treatment could revolutionize root canal disinfection
- Sonic clean boosts root canal germ kill, but pain same