Chill or zap? new study tests cold and laser to cut root canal pain

NCT ID NCT07627867

Ongoing Symptom relief Sponsor: Future University in Egypt Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using cold or laser-activated fluids during a root canal can reduce pain and kill more bacteria than standard treatment. Sixty adults with an infected lower molar will receive one of four rinses: room-temperature, cold, heated, or laser-activated sodium hypochlorite. Pain levels and bacterial counts will be measured over the next few days to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium hypochlorite (NaOCl) at different temperatures or activated by laser
What this could lead to: If successful, this could point toward a better way to reduce pain and bacteria after a root canal, making the procedure more comfortable.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The treatments are compared to standard care, and any benefit may be modest.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)

Contacts and locations

Locations

Future University in Egypt

Cairo, New Cairo, 11835, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.