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Could a simple saltwater rinse revolutionize Post-Root canal pain relief?

NCT ID NCT07701551

Not yet recruiting Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether a 3% hypertonic saline (saltwater) rinse, used at the end of a root canal procedure, can reduce pain and inflammation better than the standard 0.9% saline rinse. Forty adults with painful tooth inflammation will receive one of the two rinses, and their pain levels will be tracked for 48 hours. The goal is to find a simple, low-cost way to improve comfort after root canal treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hypertonic saline (3%)
What this could lead to
If effective, this simple, low-cost rinse could become a standard step to reduce pain after root canals.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply widely. The effect may be modest or no better than standard care.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYMPTOMATIC IRREVERSIBLE PULPITIS (SIP)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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