Ice or steroid? simple rinse could ease root canal pain

NCT ID NCT07676396

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study compares two final rinses inside the tooth after root canal treatment for people with severe tooth pain from irreversible pulpitis. One rinse is a cold saline solution (cryotherapy), the other is a steroid solution (dexamethasone). The goal is to see which better reduces pain in the first days after the procedure. Forty adults with painful lower molars will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexamethasone, cold saline, cold sodium hypochlorite

What this could lead to

If one method works better, dentists may have a simple, low-cost way to ease pain after root canal treatment.

What could go wrong

This is a small, early-phase trial with only 40 people, so results may not apply to everyone. Pain relief may be modest or similar between groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • October 6 university

    Giza, Egypt