Nutritional disorder

This study tests a once-monthly injection called berobenatide to help adults with overweight or obesity lose weight. About 954 participants will receive either the drug or a placebo for 20 months. The goal is to see if the drug is safe and effective for weight loss, including in …

This study looks at whether giving people with high blood pressure and food insecurity free food and kitchen skills training can improve their health. About 200 adults aged 35-75 will either get the program or standard care. Researchers will measure blood pressure and blood sugar…

This study tests whether giving DHA (a type of omega-3 fat) early to very preterm infants who are small at birth can improve head growth without causing too much fat gain. The trial will include 152 infants and measure head size and body fat at 36 weeks adjusted age. If successfu…

This early-stage study is testing an experimental drug, MBX 4291, in 124 adults with obesity. The main goal is to check the drug's safety and how the body processes it. Participants will receive either the drug or a placebo as a shot under the skin, and researchers will monitor f…

This pilot study tests whether a special diet based on a baby's lean body mass can help large newborns (born with excess body fat) who struggle with oral feeding. Researchers will compare this tailored feeding approach to standard care in 40 infants. The goal is to see if the die…

This study tests whether customizing the nutrients in donor breast milk helps preterm babies (born at 30 weeks or earlier, weighing under 3.3 pounds) grow better than standard fortification. Fifty infants will be randomly assigned to receive either standard or targeted fortificat…

This study compares three approaches to help pregnant women and new mothers maintain a healthy weight. About 795 participants will receive either self-management support via mobile app or mail, community-based help from health workers, or usual care. The goal is to see which meth…

This study tests whether a high-MCT (medium-chain triglyceride) formula given before and after Kasai surgery can improve growth and nutrition in infants with biliary atresia. Biliary atresia is a rare liver condition that blocks bile flow, leading to malnutrition. The trial will …

This study looks at how popular weight-loss medications (GLP-1 and GIP/GLP-1 analogs) affect what people eat, their metabolism, and behavior over a year. Researchers will track 100 adults with overweight or obesity to see changes in weight, body composition, and diet quality. The…

This study tests a school program called Strong Teens for Healthy Schools (STHS) that teaches middle school students about civic engagement, healthy eating, and physical activity. The goal is to help students improve their own health and make positive changes in their school envi…

This study tests whether giving extra protein through feeding tubes to critically ill patients on ventilators can lower the chance of death within 90 days. About 2,500 adults in ICUs will get either a high-protein or standard-protein diet starting day 5. The goal is to see if mor…

This study looks at a program called Healthy School Recognized Campus, which helps schools in Texas offer more physical activity and nutrition programs to students. About 900 kids in grades 4 through 9 will take part. Researchers want to see if the program improves kids' health, …

This study compares low-glycemic index (GI) bakery foods like pasta and pizza to standard wholegrain versions in 40 adults with high triglycerides. The goal is to see if low-GI carbs improve a key marker of metabolic and heart risk more than wholegrain carbs. Participants follow …

This study tests a once-daily pill called orforglipron in 800 adults with obesity or overweight who also have painful knee osteoarthritis. The goal is to see if the drug reduces knee pain and improves physical function over about 74 weeks. Participants will be randomly assigned t…

This study looks at whether eating a small handful of almonds (about 18 grams) 30 minutes before a meal can reduce the rise in blood sugar after eating. Researchers will test 25 adults with prediabetes, comparing blood sugar levels after meals with and without almonds. They also …

This study tests whether extra nutritional counseling helps head and neck cancer patients maintain their weight after surgery. 60 adults having surgery for head and neck cancer will be split into two groups: one gets standard care, the other gets extra support from a dietitian an…

This study tests a nutrition education program for children ages 2 to 18 recently diagnosed with celiac disease. The program focuses on eating naturally gluten-free foods and avoiding ultra-processed gluten-free options. Researchers will compare this approach to standard gluten-f…

This study tests whether remote nutritional counseling helps cancer patients stick to their treatment plan and feel better. 240 adults with invasive cancer starting therapy will receive either a single consultation with written materials or a more intensive program with monthly f…

This study tests a special infant formula designed for babies with cow's milk protein allergy. The formula includes added prebiotics, probiotics, and a human milk oligosaccharide to help ease allergy symptoms. About 41 infants under 10 months old will use the formula for 4 weeks,…

This study tests whether a 5-minute daily mouth exercise routine (PIOMI) combined with feeding at specific times of day helps preterm infants (29-33 weeks old) transition to full oral feeding and gain weight. 54 babies will be monitored for 14 days. The goal is to improve feeding…

This study tests a smartphone app designed to help cancer patients manage their nutrition. Researchers will enroll 84 people with cancer who are at risk for nutritional problems. Participants will use the app to track their diet and receive guidance from nutritionists, with the g…

This study is testing whether artificial intelligence can predict how individuals respond to different diets. Researchers will give 8,000 adults specific meal plans and measure their blood sugar, insulin, and other markers after eating. The goal is to develop algorithms that can …

This study looks at how the body's production of glucose, fat, and protein changes in critically ill patients on ventilators when they receive nutrition. Researchers will measure these changes using special labeled tracers, comparing a fasting state to a fed state. The goal is to…

This study compares two types of food labels to see which one better helps Indonesian adults spot unhealthy products. Researchers will show 1,000 participants either a nutrient warning label or the Nutri-Level label and test their ability to identify foods high in sugar, salt, or…

This study looks at how therapeutic cooling after cardiac arrest affects the body's energy expenditure and which nutrients (sugars, fats, proteins) are burned for fuel. About 40 unconscious patients will be cooled to either 33°C or 36°C and given a fixed nutrition plan. Researche…

This observational study looks at how different settings in haemodiafiltration (a type of dialysis) affect people with kidney failure. It compares high versus low fluid exchange volumes and two different sodium concentrations in the dialysis fluid. Researchers will track toxin re…

This study compares the effects of a ketogenic diet (high fat, very low carb) and a vegetarian diet (plant-based) against a standard mixed diet on gut bacteria, inflammation, and blood markers. Over 12 weeks, 200 adults aged 18-60 will provide stool and blood samples to track cha…

This study, called CEPEC, is a large platform trial enrolling 5,500 ICU patients across multiple countries. It tests different approaches to three common ICU treatments: how low to let blood pressure go with vasopressors, when to give platelet transfusions, and how to provide nut…

This study will test whether adding taxes to unhealthy foods and giving discounts on healthy foods changes what people buy in an online grocery store. About 2,239 adults from all income levels will participate, with some getting only taxes, some only subsidies, some both, and a c…

This study looks at whether giving more protein (over 1.2 grams per kilogram per day) to critically ill patients with acute kidney injury helps their kidneys recover faster or causes harm. Researchers will review medical records from 344 adults in five Argentine ICUs, comparing t…

This study follows 240 pregnant women and their babies to see if the mother's intake of certain nutrients (like choline, folate, and vitamin B12) during pregnancy is linked to the child's brain development up to age 2. Researchers will measure nutrients in the mother's blood and …

This study looks at how eating more plant foods changes the bacteria in your gut and affects your heart health. Healthy adults aged 30 to 70 who eat few plants will get all their meals from the study team for four weeks. Researchers will measure gut bacteria, blood, and other hea…

This study tests an online platform designed to help teenagers from low-income backgrounds eat healthier, be more active, and sit less. About 1000 students aged 11-16 from six schools in Central Catalonia will take part. Half will use the platform right away, while the other half…

This study aims to understand how amino acids are processed differently in critically ill patients who have been in the ICU for more than 7 days compared to healthy volunteers. Researchers will inject stable (non-radioactive) amino acid tracers and take multiple blood samples ove…

This study looks at whether warning labels on sugary drinks affect people's biases about weight. Over 500 adults will shop in a mock store and answer surveys about their beliefs regarding people with obesity. The goal is to understand potential unintended effects of nutrition lab…

This study tests a goat milk-based formula alternative (GMDFA) in 15 infants aged 8-10 weeks who cannot exclusively breastfeed. Researchers compare growth, gut health, and nutrition markers between infants fed GMDFA, undiluted goat milk, or breast milk. The goal is to see if GMDF…

This study tracks 200 patients who have had a stem cell transplant to understand their nutritional health. Researchers measure body composition, food intake, and blood protein levels over six months. The goal is to see if better nutrition leads to longer survival and fewer compli…

This study is testing whether a smartphone app can help firefighters improve their sleep, reduce stress, and boost thinking skills. About 50 firefighters will use the app and report how well it works. The goal is to see if the program is easy to use and helpful for real-life fire…

This study follows 832 children from remote farming communities in Pakistan to see how their diet and nutrition affect their growth and development up to age 5. Researchers will measure body mass index, head circumference, and developmental skills using questionnaires. The goal i…

This study looks at how different diets—vegan, vegetarian, and omnivorous—affect heart and metabolic health in adults aged 18 to 65 living in Rosario, Argentina. Researchers will measure things like cholesterol, blood sugar, body fat, and blood pressure. The goal is to understand…