Idiopathic scoliosis

This study looks back at medical records of 100 children and teens who had surgery for idiopathic scoliosis (a curved spine) using the REFLECT system. Researchers want to see how often the device's cords break and if more surgeries are needed. The goal is to understand how well t…

This study tests a new bone graft putty (MagnetOs Putty) against the standard method of using the patient's own bone to help the spine fuse after scoliosis surgery. About 140 teens and young adults with idiopathic scoliosis will take part. The goal is to see if the putty leads to…

This study tests whether a daily probiotic supplement (Bifidobacterium breve) can slow the curve progression of idiopathic scoliosis in children aged 6 to 15. One hundred participants will take the probiotic or receive lifestyle education for 6 months. Researchers will measure sp…

This study looks at whether adding a gentle back-pulling machine (traction) to special exercises can improve spine curves and reduce pain in teens with mild scoliosis. About 40 adolescents with curves between 10 and 25 degrees will be randomly assigned to get either real traction…

This study will compare two exercise approaches for teens aged 10–18 with mild idiopathic scoliosis (Cobb angle 10–25°). One group will receive a tailored exercise program with corrective moves and mirror therapy; the other will play active video games (Xbox Kinect). Researchers …

This study compares two exercise programs—core stabilization exercises and traditional rehabilitation—in 60 female adolescents (ages 11-18) with mild to moderate idiopathic scoliosis (Cobb angle 10-40°). The goal is to see which approach better improves spinal stability, posture,…

This study compares two types of back surgery for teens and young adults with scoliosis (a curved spine). One is the standard open surgery, and the other is a newer, minimally invasive approach that uses smaller cuts and advanced imaging. The goal is to see if the less invasive m…

This study explores using millimeter-wave radar and artificial intelligence to detect early signs of scoliosis by analyzing a person's gait. About 200 children and adults with suspected scoliosis will walk in front of a radar sensor, and the AI will compare its findings to standa…

This study explores whether foot pressure patterns, measured while standing and walking, can be used with machine learning to detect adolescent idiopathic scoliosis early. Researchers will collect data from 500 teens aged 10-18, including those with and without scoliosis. The goa…

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This study tests whether artificial intelligence can help teens with idiopathic scoliosis improve their posture. Thirty participants aged 10–18 will receive either standard physical therapy or additional AI-based feedback on their body alignment. The goal is to see if the AI guid…

This study tests whether a 12-week program of core and breathing exercises can improve spine curvature, breathing, and appearance in teens aged 10-17 with mild scoliosis (Cobb angle 10-25°). 32 participants will be split into two groups: one doing the special exercises, the other…

This study tests if a new pain medicine called tegileridine works as well as morphine for teenagers recovering from scoliosis surgery. About 171 teens will receive either tegileridine or morphine through a pump they control. Researchers will compare pain levels and side effects o…

This study tests whether Mat-Pilates exercises can improve balance and walking ability in adolescents aged 12 to 15 with mild scoliosis (curves between 10 and 25 degrees). Forty participants will be randomly assigned to either Mat-Pilates or standard physical therapy. The goal is…

This pilot study will test whether a 'Comfort Tote' filled with items like aromatherapy oils, stress balls, acupressure guides, and a journal can help teens aged 10-21 feel less pain, anxiety, and stress after scoliosis surgery. Half the participants will get a tote with therapeu…

This study tests whether wearing a custom-made back brace, along with standard care like physical therapy, can reduce low back pain in adults with degenerative scoliosis (a curved spine that causes pain). About 130 people aged 40 to 75 with moderate to severe pain will be randoml…

This study looks at whether adding a simple manual diaphragm release to standard Schroth exercises can improve breathing, posture, and quality of life in adolescents with idiopathic scoliosis. Forty-two teens aged 10–18 will be randomly assigned to either Schroth exercises alone …

This study tests whether adding low-dose ketamine to standard morphine pain pumps helps teens use less morphine after scoliosis surgery. About 114 patients aged 10-18 will be randomly assigned to get either the combo or morphine alone. The goal is to see if the combo reduces opio…

This study looks at whether adding Kinesio Taping to Schroth therapy helps reduce back pain and improve daily function in young adults (ages 18-30) with mild idiopathic scoliosis. Participants will be split into three groups: one gets Schroth therapy plus real Kinesio Taping, one…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study compares two exercise programs—Schroth and Scientific Exercise Approach to Scoliosis—to see which better corrects spine curves in teens with mild scoliosis. About 30 teenagers aged 13 to 18 with curves between 10 and 25 degrees will participate. The goal is to find the…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study translates and tests a Turkish version of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQAIS), a tool designed to measure body image and perceived deformity in teens with scoliosis. Researchers will enroll 100 adolescents aged 10–19 with idiopat…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study looks at adults aged 25-40 who had surgery for scoliosis as teenagers, comparing them to people with scoliosis who didn't have surgery and to healthy individuals. Researchers want to understand how the surgery affects daily life, pain, breathing, and quality of life ma…

This study checks if a questionnaire called BREQ-2 is a good tool to measure exercise motivation in teens with scoliosis. About 95 adolescents aged 10-19 who have been doing scoliosis exercises for at least 2 months will fill out online surveys. The goal is to see if the question…

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…

This study aims to translate and test a questionnaire called SCaRES into Turkish. The questionnaire measures the emotional and behavioral impact on parents or caregivers of children with scoliosis. Researchers will enroll 23 caregivers to see if the Turkish version is reliable fo…

This study aims to translate a questionnaire that asks teens with scoliosis how they feel about their body's front appearance into Turkish. About 29 adolescents with idiopathic scoliosis will take the survey. The goal is to make sure the Turkish version is reliable and accurate, …

This study looks at whether teenagers with severe scoliosis have trouble sensing where their body is in space (proprioception). Researchers will compare brain scans and muscle measurements of 60 teens with scoliosis to healthy controls. The goal is to understand if these issues a…

This study will look at 30 teens aged 12-20 with thoracic adolescent idiopathic scoliosis to see if the type of spinal curve affects their breathing, exercise ability, and sleep quality. Participants will be grouped by curve pattern (T-type or TL-type) and undergo standard tests …