Idiopathic scoliosis
MONDO:0000726A scoliosis with no known cause.
182 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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AI app takes on scoliosis: could your phone replace physical therapy?
Disease control OngoingThis study tests whether a smartphone app that uses artificial intelligence can help teens with scoliosis do better exercises than traditional physical therapy. The app analyzes posture and creates a personalized workout plan. Researchers will compare spine curve changes and how …
Phase: NA • Sponsor: Jinan University Guangzhou • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Casting vs bracing: which works best for kids with curved spines?
Disease control OngoingThis study compares two treatments—casting and bracing—for children under 3 with early-onset scoliosis. The goal is to see which method better controls spine curvature and improves quality of life. About 71 children and their parents are taking part.
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New spine surgery aims to straighten scoliosis in teens
Disease control OngoingThis study tests a spine surgery for 20 teenagers (ages 12-21) with a specific type of scoliosis called Lenke 1. The goal is to correct the spine curve and improve quality of life. Researchers will measure how well the surgery works using X-rays and patient questionnaires.
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Spine-Tethering device aims to straighten scoliosis without fusion
Disease control TerminatedThis study was designed to test a device called the Globus Reflect Tether for children and teens with scoliosis who are still growing. The device is surgically attached to the spine to hold the curve in place, allowing the other side to grow and gradually straighten the spine. Th…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New spinal brace implant tracked for 5 years in teens
Disease control OngoingThis study follows 200 teens with scoliosis who received the MID-C implant, a device that acts like an internal brace to straighten the spine. Researchers will check if the spine stays corrected (curvature under 40 degrees) and monitor for any safety issues over 5 years. The goal…
Phase: NA • Sponsor: Apifix • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a 3D scanner replace X-Rays for scoliosis checks?
Diagnosis OngoingThis study tests a 3D body scanner called NSite to see if it can reliably monitor scoliosis in teenagers. Thirteen teens with scoliosis will be scanned by three different users to check if the results are consistent. If it works, this device could offer a radiation-free way to tr…
Sponsor: Stanford University • Aim: Diagnosis
Last updated Jun 27, 2026 13:05 UTC
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Teens with scoliosis try futuristic balance trainer in new study
Symptom relief OngoingThis study looks at whether adding special balance training to standard scoliosis exercises can improve balance in teenagers with mild scoliosis. About 72 teens aged 10-17 will either use a high-tech platform that gives real-time feedback or do simple balance exercises at home. T…
Phase: NA • Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Video games vs. standard rehab: a new hope for scoliosis recovery?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether playing active video games can help teenagers regain balance and posture better than standard exercises after scoliosis surgery. About 51 teens who had spinal fusion will be split into three groups: video game training, standard stabilization exercises…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Stretching before surgery: could simple exercises improve scoliosis outcomes?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether doing special flexibility exercises for 6 months before spinal fusion surgery helps teens with scoliosis. Researchers want to see if it leads to fusing fewer vertebrae, better curve correction, shorter surgery, and less time in the hospital. Forty teens a…
Phase: NA • Sponsor: Eric Parent • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Opioid-Free pain control for teens after scoliosis surgery: a safer way?
Symptom relief ENROLLING_BY_INVITATIONThis study compares a new opioid-free pain management plan to the usual opioid-based approach for teenagers (ages 10-20) having spinal fusion surgery for scoliosis. The opioid-free plan uses a mix of numbing injections and non-opioid medications like gabapentin, ibuprofen, and ac…
Phase: PHASE4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New hope for teens: could a simple infusion cut opioid use after spine surgery?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether adding a low-dose dexmedetomidine infusion to standard pain management can lower the amount of narcotics needed and reduce side effects like nausea and itching in teenagers having posterior spinal fusion for scoliosis. About 160 adolescents with idiopa…
Phase: PHASE4 • Sponsor: Nichole Doyle • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Weekly Check-Ins could boost patient satisfaction for chronic pain
Knowledge-focused TerminatedThis study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can a special clinic get workers back on the job faster? norway launches massive study.
Knowledge-focused OngoingThis study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…
Phase: NA • Sponsor: Nordlandssykehuset HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Could a Lying-Down scan replace standing X-Rays for scoliosis?
Knowledge-focused OngoingThis study tests whether a special type of X-ray called DXA, taken while lying down, can measure spine curves as well as standard standing X-rays in people with scoliosis. About 20 participants will have both types of images taken, and researchers will compare the results and ask…
Phase: NA • Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Walking test could revolutionize scoliosis checks in kids
Knowledge-focused OngoingThis study aims to develop a new way to measure how the spine moves during walking in children, both healthy and those with scoliosis. Researchers will use a special camera system and reflective markers placed on the skin to track movement. The goal is to create a reliable and ea…
Phase: NA • Sponsor: IRCCS Eugenio Medea • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Spine curve study: surgery vs. no surgery – which works better?
Knowledge-focused OngoingThis study follows nearly 2,000 adults with spinal deformity (curved spine) to compare outcomes between those who have surgery and those who do not. Researchers track X-rays, pain levels, and quality of life over time. The goal is to learn which approach leads to better long-term…
Sponsor: International Spine Study Group Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Massive PT study mines 4 million records to find what works best
Knowledge-focused OngoingThis study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …
Sponsor: ATI Holdings, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Phone app vs. doctor: can a mobile tool catch infections after surgery?
Knowledge-focused TerminatedThis study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Could sleep problems worsen scoliosis in kids? new study investigates
Knowledge-focused OngoingThis study looks at whether sleep-disordered breathing, like obstructive sleep apnea, is linked to worsening spine curves in children with idiopathic scoliosis. Researchers will follow 405 children aged 6 to 15 with mild to moderate scoliosis. They will measure spine curves and s…
Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Teen scoliosis study aims to unlock secrets of spine movement and balance
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how the way the lower back and pelvis move together (lumbopelvic rhythm) impacts balance, daily activities, and quality of life in 50 adolescents aged 10-18 with idiopathic scoliosis. Researchers will use motion sensors and balance platforms to measure these m…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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AI tool aims to take guesswork out of scoliosis treatment
Knowledge-focused OngoingThis study tests a computer program designed to help doctors choose the best rehabilitation plan for teens with idiopathic scoliosis. Doctors will first make treatment decisions as usual, then see what the computer suggests for the same patients three months later. The goal is to…
Phase: NA • Sponsor: Istituto Scientifico Italiano Colonna Vertebrale • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Spine surgery fluid study pulled before starting
Knowledge-focused TerminatedThis study was designed to see if a special saltwater solution (buffered 2% hypertonic saline) is better than standard fluids for children and teens having spine surgery for scoliosis. The goal was to compare how the body's acid-base balance and electrolyte levels changed during …
Phase: PHASE2, PHASE3 • Sponsor: Joseph D. Tobias • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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One exercise may help scoliosis – but Don't get excited yet
Knowledge-focused OngoingThis study tests whether a single session of a self-corrective exercise can immediately improve muscle activity and spinal alignment in 40 adolescents with idiopathic scoliosis. Participants do both a standard exercise and the self-corrective exercise, and researchers measure cha…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Teens' genes may predict pain after back surgery
Knowledge-focused OngoingThis study looks at how a child's genes and emotions influence pain after major spine surgery. Researchers will follow 880 teens aged 10-18 having spine fusion for scoliosis or similar conditions. They will measure pain levels, breathing problems, and nausea after surgery, and ch…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Standing on a mat could reveal clues about scoliosis
Knowledge-focused OngoingThis study looks at 84 teens with scoliosis to see if the way they put pressure on their feet is linked to the shape of their spine curve. Participants simply stand on a pressure-sensing mat while doctors also check their spine X-rays. The goal is to better understand how scolios…
Sponsor: Mahmoud Ibrahim Elsayed Aly Mahmoud • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:59 UTC