Opioid-Free pain control for teens after scoliosis surgery: a safer way?

NCT ID NCT06935331

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new opioid-free pain management plan to the usual opioid-based approach for teenagers (ages 10-20) having spinal fusion surgery for scoliosis. The opioid-free plan uses a mix of numbing injections and non-opioid medications like gabapentin, ibuprofen, and acetaminophen. Researchers will measure pain levels, opioid use, hospital stay length, and any side effects to see if avoiding opioids works just as well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
multimodal opioid-free pain regimen (clonidine, epinephrine, ropivacaine, toradol, gabapentin, ibuprofen, acetaminophen, diazepam)
What this could lead to
If successful, this could offer a safer, opioid-free way to manage pain after scoliosis surgery in teens, reducing the risk of opioid dependence and side effects.
What could go wrong
This is a small, single-center Phase 4 trial with only 58 participants, so results may not apply broadly. The opioid-free regimen may not control pain as effectively as traditional opioids for some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OrthoCarolina Research Institute

    Charlotte, North Carolina, 28207, United States

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