Teens' genes may predict pain after back surgery
NCT ID NCT02998138
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how a child's genes and emotions influence pain after major spine surgery. Researchers will follow 880 teens aged 10-18 having spine fusion for scoliosis or similar conditions. They will measure pain levels, breathing problems, and nausea after surgery, and check for long-term pain. The goal is to understand why some kids have more pain than others, which could help doctors personalize pain treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to better ways to predict and manage pain in children after major surgery, potentially reducing opioid use.
What could go wrong
This is an observational study, not testing a treatment. It may not directly change patient care, and results might not apply to all children.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke Children's Hospital
Durham, North Carolina, 27710, United States
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Johns Hopkins Hospital
Baltimore, Maryland, 21205, United States
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Stanford University Hospital
Stanford, California, 94305, United States
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The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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University of Mississippi Medical Center
Jackson, Mississippi, 39216, United States