SCOLIOSIS

This trial tests a new implantable device called ThecaFlex DRx in 90 people with spinal muscular atrophy (SMA) who cannot receive standard spinal injections due to spine problems or other risks. The device is placed under the skin and delivers the medication nusinersen directly i…

This study tests a new device called the VersaTie system, used during spine fusion surgery to help prevent a complication called proximal junctional failure. The trial will enroll 225 adults with spinal deformities like scoliosis or kyphosis who need surgery on five or more verte…

This study looks at whether adding a structured yoga program to usual care can reduce back pain and improve quality of life for teens with scoliosis. About 500 participants aged 10-20 who are not having surgery will be randomly assigned to standard care or standard care plus yoga…

This study looks at adults with two types of scoliosis (idiopathic and degenerative) to understand what physical problems they have that physical therapy might help. Researchers will compare them to healthy adults using surveys and physical exams. The goal is to gather informatio…

This study looks at 600 teens and young adults (ages 14-26) with conditions like juvenile arthritis, fibromyalgia, or past surgeries to understand why some develop long-lasting pain while others don't. Researchers will examine pain sensitivity, immune markers, and social factors …

This study is testing a new way to measure balance in adults with spinal deformity (like scoliosis). Researchers will use a 'functional reach test' where participants reach forward and sideways while wearing motion sensors. The goal is to give surgeons better information about ba…

This study records conversations between doctors, patients, and families to understand how decisions are made about scoliosis treatment. Researchers will use these videos to create a tool that helps patients choose between surgery or simply watching the curve. The study includes …

This study looks at whether men and women with scoliosis experience pain differently when pressure is applied to the spine using a physiotherapy roller. Fifty adults with scoliosis will do a six-week exercise program, and their pain and function will be measured with a standard s…

This study measures how hard children with conditions like neuromuscular disease, scoliosis, or heart problems work to breathe. Researchers use a thin tube placed through the nose into the esophagus to measure breathing muscle strength and effort. The goal is to better understand…

This study is tracking 500 adults with complex spinal deformities (like scoliosis or kyphosis) who undergo minimally invasive surgery. Researchers will measure pain, disability, and quality of life over time to find the best surgical approaches and reduce complications. The goal …

This study is following 1,500 adults with complex spine problems (like scoliosis or kyphosis) who are having surgery. Researchers want to learn which surgical methods work best and how to reduce complications. Participants will complete surveys about pain and quality of life, and…

This study is testing how accurately the eCential Robotics robot helps surgeons place screws in the spine. About 45 people aged 5 and older who need spine surgery will take part. The robot uses 3D imaging and navigation to guide screw placement, and the study will measure screw a…

This study follows 140 female dancers aged 11-16 who have scoliosis (a curved spine) and dance at least three times a week. Researchers will check their muscles, bones, flexibility, and spine every six months for three years. Some dancers will also do a special core-strengthening…