Could a ketamine cocktail cut opioid use after spine surgery?
NCT ID NCT07452705
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding low-dose ketamine to standard morphine pain pumps helps teens use less morphine after scoliosis surgery. About 114 patients aged 10-18 will be randomly assigned to get either the combo or morphine alone. The goal is to see if the combo reduces opioid use and side effects while keeping pain under control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine and Morphine (combined in a patient-controlled pump)
What this could lead to
If it works, this could offer a safer way to manage pain after scoliosis surgery, reducing opioid use and side effects like nausea or drowsiness.
What could go wrong
This is a small, early-phase trial (114 participants) that hasn't started yet. The benefit may be small or not apply to all patients, and ketamine can cause side effects like hallucinations.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
Contact Phone: •••-•••-•••• Email: •••••@•••••