New pain drug could replace morphine for teens after back surgery
NCT ID NCT07229495
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests if a new pain medicine called tegileridine works as well as morphine for teenagers recovering from scoliosis surgery. About 171 teens will receive either tegileridine or morphine through a pump they control. Researchers will compare pain levels and side effects over the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tegileridine
What this could lead to
If it works, this could offer a new pain relief option for teenagers after spinal surgery, potentially with fewer side effects than morphine.
What could go wrong
This is a Phase 4 trial, but it's still early and small (171 participants). The new drug may not be as effective or safe as hoped, and side effects are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Beijing Chao-yang Hospital, Capital Medical University
Beijing, 100020, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Henan Provincial People's Hospital
Zhengzhou, Henan, 450003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Peking Union Medical College Hospital
Beijing, 100730, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Shanghai Children's Medical Centre, School of Medicine, Shanghai Jiao Tong University
Shanghai, 200127, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330006, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, 200092, China
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••