Tanta University

This study is testing whether erdosteine, a drug already used for other conditions, can safely reduce fat buildup and scarring in the liver of people with nonalcoholic fatty liver disease (NAFLD). About 50 adults with fatty liver will take the drug and be monitored for changes in…

This study tests whether silymarin, a natural antioxidant from milk thistle, can protect brain cells and help manage symptoms in people with Parkinson's disease. Fifty adults aged 45–65 who are already on standard Parkinson's medication will take silymarin alongside their usual t…

This study tests if nicorandil, a heart medication, can reduce inflammation and improve symptoms in people with active rheumatoid arthritis. About 46 adults who are already on standard arthritis drugs will take nicorandil for 3 months. Researchers will measure joint swelling, pai…

This study tests whether carbocisteine, a drug already used for coughs, can help people with nonalcoholic fatty liver disease (NAFLD). About 46 adults with fatty liver will take the drug to see if it reduces fat buildup in the liver. The goal is to find a safe, affordable treatme…

This study tests whether vinpocetine, a supplement that may improve blood flow and reduce inflammation, can safely help control Parkinson's disease symptoms. Researchers will measure changes in movement and daily function using a standard rating scale, and also check blood marker…

This study tests whether the drug cabergoline can prevent ovarian hyperstimulation syndrome (OHSS), a serious complication of fertility treatments. About 150 women at high risk for OHSS will receive either cabergoline or standard care (coasting). The goal is to see which approach…

This study tests whether a newer acid-blocking drug (P-CAB) works better than a standard one (PPI) when used as part of a 4-drug therapy for H. pylori infection. About 320 adults who have not been treated before will take one of the two combinations. The goal is to see which trea…

This study tests whether cilostazol, a drug used for blood flow, can reduce fat buildup and scarring risk in the liver. About 50 adults with fatty liver disease will take the drug and be monitored. The goal is to see if it can control the disease and prevent it from getting worse…

This study tests whether metformin, a standard diabetes medication, can safely improve movement and quality of life in people with Parkinson's disease. Researchers will enroll 60 adults aged 50 and older who are already taking standard Parkinson's medication. The study measures c…

This study tests whether celecoxib, an anti-inflammatory drug, can help control symptoms of Parkinson's disease. Researchers will enroll 80 adults with Parkinson's to see if the drug improves movement and daily function. The goal is to reduce brain inflammation that may worsen th…

This study tests if eggshell powder works as well as standard materials (Biodentine and MTA) for treating deep cavities in children's baby molars. About 30 children will receive one of the three treatments during a pulpotomy, where the infected pulp is removed. The goal is to see…

This study looks at whether giving levothyroxine (a thyroid hormone medication) to children aged 4-15 with mild underactive thyroid (subclinical hypothyroidism) can improve how well their hearts pump blood. Researchers will measure heart function before and after treatment in 40 …

This study compares two surgical techniques for treating a narrowed urethra in women. One method uses a graft from the inner cheek, the other from the labia. The goal is to see which graft leads to better urine flow. The study will involve 40 female participants with non-traumati…

This study tests whether pentoxifylline, an anti-inflammatory drug, can help control rheumatoid arthritis. About 50 adults with active arthritis who are already on standard medications will receive pentoxifylline. The main goal is to see if it lowers disease activity scores.

This study tests whether a newer acid-blocking drug (vonoprazan) works better than standard treatment for H. pylori infection, a common stomach bacteria that can cause ulcers and cancer. About 66 adults with confirmed H. pylori will receive either vonoprazan or a standard PPI, pl…

This study tests if dapagliflozin, a drug used for diabetes, can prevent heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. About 46 adults with early-stage breast cancer who have not had chemo before will take dapagliflozin or a placebo during th…

This study tests whether adding the deworming drug mebendazole to standard mesalamine treatment can safely improve symptoms in people with mild-to-moderate ulcerative colitis. Researchers will measure changes in disease activity, blood markers, and symptom scores over time. The t…

This study tests whether an ondansetron lozenge works as well as an IV to prevent shivering in children aged 4 to 15 having their tonsils removed. Shivering is a common side effect after anesthesia. The trial will enroll 210 children and also check for nausea, vomiting, and tempe…

This study compares two ways of giving the drug ondansetron (a lozenge that dissolves in the mouth versus an injection into a vein) to prevent shivering in women having a cesarean section. About 90 women will take part. The goal is to see which method works better at stopping shi…

This study tests whether the drug duloxetine can prevent pancreatitis (inflammation of the pancreas) after a procedure called ERCP, which is used to diagnose and treat bile duct problems. About 44 adults with bile duct disease will receive duloxetine before the procedure to see i…

This study tests whether ondansetron, a drug often used for nausea, can prevent pancreatitis after a procedure called ERCP. Pancreatitis is a common and serious complication of ERCP. The trial will enroll 44 adults and compare those who get ondansetron to those who do not, checki…

This study tests whether giving ondansetron through a vein or near nerves works better to prevent vomiting and pain after laparoscopic sleeve gastrectomy. About 482 adults having this weight-loss surgery will take part. The goal is to find which method provides better relief from…

This study tests two pain-relief methods for women having a C-section: a nerve block (TFP block) and a spinal medication (dexmedetomidine). The goal is to see which provides better pain control and reduces the need for morphine. Fifty women will participate, and their pain levels…

This study looks at whether injecting botulinum toxin-A (like Botox) into the bladder can help children under 18 who have trouble urinating or wet the bed at night and haven't gotten better with standard treatments. The goal is to see if it improves symptoms and to track any side…

This study tests whether adding empagliflozin, a diabetes drug, can reduce weight gain and other metabolic problems caused by olanzapine in people with schizophrenia. About 40 adults aged 18–60 who take olanzapine will receive either empagliflozin or a placebo for several weeks. …

This study compares three common drugs—theophylline, sumatriptan, and gabapentin—to see which works best for treating post-dural puncture headache, a severe headache that can occur after a spinal tap or epidural. About 75 adults aged 21 to 50 with moderate to severe headache will…

This study tests whether a targeted ultrasound-guided nerve block can lower the body's stress response and improve pain control in adults having umbilical hernia repair. One hundred participants will receive either the block or standard care. The goal is to see if this approach r…

This study tests two different types of nerve blocks to see which one controls pain better after open-heart surgery. Researchers will measure how much pain medication patients need in the first 24 hours. The goal is to find a safer, more effective way to manage pain and reduce re…

This study tests whether fenofibrate, a drug used for high cholesterol, can reduce nerve damage (peripheral neuropathy) caused by standard chemotherapy for multiple myeloma. About 44 newly diagnosed patients will receive either chemotherapy alone or chemotherapy plus fenofibrate.…

This study tests whether giving children oral melatonin or a nebulized medicine called dexmedetomidine before tonsil surgery can reduce confusion and agitation when they wake up. About 96 children aged 3 to 7 will take part. The goal is to find a better way to help kids recover c…

This study looks at whether adding biofeedback (a way to learn how to control muscles) to standard bladder training helps children with dysfunctional voiding (trouble peeing normally). About 124 children under 18 will take part. The goal is to see which approach works better for …

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain drug) for reducing pain and anxiety after spine surgery. About 105 adults aged 21-60 having elective spine surgery will be randomly assigned to receive one of the two medicines.…

This study tests whether giving the drug dexmedetomidine at different times before surgery can lower the body's stress response when a breathing tube is placed. About 45 adults having surgery will be randomly assigned to receive the drug at different times. The goal is to see if …

This study tests whether adding roflumilast, an anti-inflammatory drug, to standard antidepressants can better reduce depression symptoms. About 60 adults with major depression who still have significant symptoms will take either roflumilast or a placebo for 8 weeks. The main goa…

This study tests two different numbing injections to see which one controls pain better after hypospadias repair in boys aged 1 to 5 years. One injection targets a nerve area near the tailbone, the other targets a different spot in the lower back. Researchers will measure pain le…

This study tests three different medicines (empagliflozin, acetazolamide, and metolazone) added to standard diuretics in 66 adults hospitalized with acute heart failure and fluid overload. The goal is to see which combination helps the body get rid of extra fluid most effectively…

This study tests whether giving calcitonin soon after a spinal cord injury can lower the chance or severity of nerve pain that often follows. Researchers will enroll 126 adults with recent spinal cord injuries and track their pain levels for up to a year. The goal is to see if ea…

This study tests a nerve block called MTP against standard patient-controlled pain medication (PCA) in 40 adults having scoliosis surgery. The goal is to see which method provides better pain control and reduces the need for extra painkillers. Participants will have their pain le…

This study tests whether dapagliflozin, a medicine normally used for diabetes, can help reduce symptoms of depression in adults. Researchers will enroll 60 people with major depression who have not responded well to standard treatments. The goal is to see if the drug improves moo…

This study tests whether fexofenadine, a common allergy medication, can improve quality of life for people with Parkinson's disease who are already on standard treatment. Researchers will enroll 46 adults aged 50 and older with mild to moderate Parkinson's. The goal is to see if …

This study tests whether adding the antihistamine desloratadine to standard treatment (mesalamine) can reduce inflammation and disease activity in people with mild to moderate ulcerative colitis. About 44 adults aged 18 to 65 who are already on mesalamine will take either deslora…

This study compares two types of pain blocks (Quadro-Iliac Plane Block and Erector Spinae Plane Block) given after total hip replacement. The goal is to see which one delays the need for extra pain medicine and reduces total morphine use. About 76 adults having hip replacement un…

This study looks at how a dental procedure called Deep Marginal Elevation (DME) affects the gums and bone around a tooth. Researchers will collect fluid from the gums and take X-rays to check for inflammation and bone changes. The goal is to understand how DME impacts oral health…

This study aims to find out why some people with rheumatoid arthritis have trouble swallowing. Researchers will use a small camera to look at the throat and voice box in 137 adults with RA. The goal is to identify factors that predict swallowing difficulty and see if the camera t…

This study compares three different ways to clean the bowel before a colonoscopy to see which works best, causes fewer side effects, and is easier for patients. About 450 adults will be randomly assigned to one of the three methods. The goal is to improve the experience and succe…

This study measures two substances in the blood (endocan and copeptin) of 40 premature babies who have respiratory distress syndrome. The goal is to see if these markers can help predict how severe the breathing problem will be. The findings may help doctors better understand and…