Centre Hospitalier Universitaire, Amiens

This study is testing whether adding an inhaled antibiotic called ARIKAYCE® to standard oral drugs works better for treating Mycobacterium xenopi lung infections. It will enroll 190 adults with this specific infection to see if the inhaled drug helps clear the bacteria from the l…

This study is comparing two ways to help children with overactive bladder, a condition that causes frequent, urgent bathroom trips and sometimes accidents. Researchers want to see if a device that gently stimulates a nerve in the ankle works as well as the standard medication, ox…

This study is testing whether it's safe to stop antibiotics early in elderly patients hospitalized with viral lung infections. Researchers want to see if reducing unnecessary antibiotic use leads to fewer side effects and similar recovery outcomes. The trial involves 256 patients…

This study is testing whether azithromycin works as well as clarithromycin for treating Mycobacterium avium complex (MAC) lung infections. Both drugs are given with two other antibiotics. Researchers want to see if azithromycin is just as effective but causes fewer side effects, …

This study is testing if attaching a clear cap to the tip of an endoscope helps doctors find and stop severe upper stomach bleeding more quickly and successfully. It will involve 72 adult patients who come to the hospital with this type of emergency bleeding. The goal is to see i…

This study is testing if using a bedside urine sensor to guide a common water pill (furosemide) is better than the usual approach for managing fluid overload after heart surgery. Researchers will compare how well the sensor-guided method removes excess fluid and whether it leads …

This study is testing whether placing specific plants in hospital laboratory rooms can reduce staff exposure to formaldehyde, a toxic chemical used to preserve tissue samples. Researchers will measure formaldehyde levels in the air and in workers' urine before and after installin…

This study aims to find a better way to quickly diagnose septic shock, a life-threatening complication of infection. Researchers will measure levels of a protein called Vasorin in the blood of 144 intensive care patients with different types of shock. They want to see if Vasorin …

This study is testing if a simple, quick finger-prick blood test (CRP point-of-care test) can predict a dangerous complication called an anastomotic leak after planned colon surgery. Researchers want to see if tracking the test results over the first five days after surgery can s…

This study is testing a new, faster type of heart MRI scan that uses artificial intelligence (AI) to create images. Researchers want to see if this quick scan is just as good as the standard, longer scan at measuring how well the heart pumps in people with a thickened heart muscl…

This study is testing a simple blood test to find children with a common inherited condition that causes very high cholesterol. Finding it early allows families to start healthy habits and safe, effective treatments to prevent heart attacks and strokes in adulthood. The goal is t…

This study is testing if a smartwatch can find a dangerous irregular heartbeat that often happens silently after heart surgery. About 324 patients who just had heart surgery will be randomly assigned to either use a smartwatch for monitoring or receive the hospital's usual care. …

This study is testing how accurately a new surgical robot can place screws in the spine during surgery. It will involve 45 patients aged 5 and older who need spinal surgery at a hospital in Amiens, France. The main goal is to collect data on the robot's safety and performance to …

This study is testing a new blood marker called p-Tau217 to see if it can accurately diagnose Alzheimer's disease. Researchers will compare results from this blood test to the current standard method, which requires a spinal tap to collect fluid. The goal is to find a simpler, le…

This study is testing whether a new AI-powered video camera system can better protect elderly people from the dangers of falling at home compared to standard emergency call buttons (telealarms). It will involve 395 people aged 75+ who are at high risk of falling and are returning…

This study tests whether an inhaled medication given around the time of surgery can prevent breathing complications in lung cancer patients having lung removal surgery. It focuses on adults with lung cancer who are at high risk for these complications because they have reduced lu…

This study is testing whether using a virtual reality headset showing calming, hypnotic scenes can help reduce anxiety, pain, and resistance in people with Alzheimer's disease during personal hygiene care like bathing. It will compare this VR approach to standard care in 24 patie…

This study is testing whether using immersive virtual reality (VR) can help reduce discomfort for patients recovering from major surgery in a surgical intensive care unit (ICU). Researchers will enroll 194 adults who have had major heart, chest, or abdominal surgery and are expec…

This study is testing whether a handheld breathing device called an OPEP can improve the day-to-day quality of life for people with bronchiectasis, a chronic lung condition. It will involve 60 children (aged 8+) and adults who are not currently using this type of device. Research…

This study aims to understand why some patients with multiple myeloma respond better to CAR-T cell therapy than others. Researchers will analyze a specific type of immune cell, called a monocyte, in about 25 patients before and after they receive CAR-T treatment. The goal is to f…

This study aims to compare two different ultrasound software systems used to measure heart function in patients with septic shock, a life-threatening infection. Researchers will analyze existing heart scan data from 60 critically ill patients to see if the two software programs g…

This study aims to understand how the drug clozapine, used to treat psychosis in Parkinson's disease, affects the body's immune system over time. Researchers will follow 24 Parkinson's patients for a year, measuring their immune cell and antibody levels. The goal is to gather inf…

This study aims to better understand the eye and vision problems that often occur in people with craniosynostosis, a condition where the bones in a baby's skull fuse together too early. Researchers will look back at the medical records of 65 patients treated at Amiens University …

This study aims to understand the two-way relationship between pregnancy and inflammatory bowel diseases (IBD) like Crohn's and ulcerative colitis. Researchers will follow 945 women from a health registry to track how often their IBD symptoms flare up during pregnancy and after g…

This study aims to better understand the genetic causes of orofacial clefts (cleft lip and palate) using advanced optical genome mapping technology. Researchers will examine DNA from 26 participants with clefts who don't have an existing genetic diagnosis. The goal is to identify…

This study aims to learn more about a procedure called TIPS, which is used to treat severe complications of high blood pressure in the liver. Researchers will look back at medical records to compare how well the TIPS procedure works and how safe it is for patients with a rare liv…

This study aims to find early signs from brain scans that can predict whether patients with recurrent glioblastoma (an aggressive brain cancer) will survive at least 6 months while taking the drug bevacizumab (Avastin). Researchers will scan patients' brains shortly after startin…

This study aims to understand how the normal support cells in bone marrow (called mesenchymal stem cells) might help the cancer cells in Waldenström disease survive and grow. Researchers will compare these cells from 50 patients who need treatment to cells from healthy people. Th…

This study aims to better understand a severe and complex type of heart failure called mixed cardiogenic-vasoplegic shock. Researchers will look back at the medical records of 2,500 patients from three French hospitals to see how many survive and what factors lead to worse outcom…

This study aims to gather information on how well different blood-thinning medications work for cancer patients who develop clots in their surface veins. Researchers will observe over 1,500 adult cancer patients with these clots to see which treatments are linked to fewer recurri…

This study aims to understand how language develops in people with Williams Syndrome, a rare genetic condition. Researchers will use brain scans (EEG-NIRS) and questionnaires to see if heightened sensitivity to sound plays a key role in their language abilities. The study will co…

This study aims to understand how pesticide exposure might be linked to endometriosis, a painful condition that can cause infertility. Researchers will compare 160 women with and without endometriosis, measuring stress markers in their blood and analyzing the bacteria in their gu…

This study looks back at medical records to see if the amount of IV fluids a mother receives during labor is linked to how much weight her newborn loses in the first two days. It focuses on babies who are fed only formula. The goal is to better understand this common weight loss …

This study aims to better understand what causes dangerous blood clots in people with antiphospholipid syndrome (APS). Researchers will measure levels of a specific protein, called annexin A2, on the surface of immune cells (monocytes) in 60 adults with APS. The goal is to see if…

This study aims to see if a simple blood test can predict whether a rare blood cancer called Waldenström's disease will come back after treatment. Researchers will test 90 patients who have finished their first 6 months of therapy. The goal is to learn if tiny pieces of cancer DN…

This study aims to understand if severe pain experienced just before emergency surgery increases the risk of developing long-term chronic pain after the operation. Researchers will follow 693 adults undergoing emergency bone or abdominal surgery in France. The goal is to identify…

This study aims to understand how brain stimulation might help people move faster after a stroke. Researchers will first test a brain stimulation technique on 60 healthy people to see how it affects reaction times. Then, they will apply the same technique to 20 stroke patients to…

This study aims to discover the unknown genetic causes of congenital sideroblastic anemia, a rare disorder where the body struggles to make healthy red blood cells. Researchers will analyze the complete genetic code of 20 patients whose condition has no known genetic explanation.…

This study aims to understand if certain inherited genetic variations are linked to unexplained strokes, particularly in younger adults. Researchers will compare the genes and blood markers of 240 adults who have had a stroke with no clear cause. The goal is to gather knowledge t…

This study aims to better understand how blood sugar levels vary in women with different types of polycystic ovary syndrome (PCOS). Researchers will use continuous glucose monitors to track sugar levels in 80 women with PCOS. The goal is to see if certain PCOS types have healthie…

This study aims to understand why people with lupus often show false-positive results on certain antibody tests that check for organ transplant compatibility. Researchers will examine blood samples from 30 adult lupus patients who have never been pregnant, had transfusions, or re…

This study aims to understand the long-term outcomes for women who froze eggs or ovarian tissue before cancer treatment. Researchers will track over 100 female cancer survivors to see if and how they use their preserved fertility options, and what factors influence their family-b…