Scientists hunt for hidden genes behind cleft lip and palate
NCT ID NCT03065686
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study aims to find genetic factors that may cause cleft lip and palate. Researchers will analyze the DNA of 30 people with the condition using advanced sequencing. The goal is to better understand the genetic roots of this birth defect, which could inform future research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify new genes involved in cleft lip and palate, potentially guiding future research or risk assessment.
- What could go wrong
- This is a small, early-stage genetic study with only 30 participants. It is not testing a treatment, so it may not lead directly to any therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Nov 2016
- Expected to finish
-
Nov 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject with a NSCL/P or CL/P of unknown etiology, * national health care insurance holders Exclusion Criteria: * Subject with a CL/P of known etiology, * Subject with a NSCL/P and an IRF6 mutation
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cleft lip and palate are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
CHU Amiens Picardie
RECRUITINGAmiens, 80054, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a nerve block Add-On calm pain and agitation after cleft palate repair?
- Can the pace of speech therapy make a difference for kids with cleft palate?
- Could a phone app help parents of kids with special needs thrive?
- Baby teeth stem cells may spare kids a second surgery for cleft palate repair
- Tailored Pre-Surgery care may improve outcomes for babies with cleft lip and palate
- New 3D face scans could help babies with cleft lip