Could a transplant drug shrink dangerous blood vessel tangles?
NCT ID NCT02042326
First seen May 16, 2026 · Last updated May 21, 2026 · Updated 2 times
Summary
This study tests whether sirolimus, a drug used to prevent organ rejection, can reduce the size and symptoms of severe arteriovenous malformations (AVMs) — tangled blood vessels that can cause pain, bleeding, and other problems. About 50 people aged 2 and older with advanced AVMs will take sirolimus by mouth for a year. Researchers will measure changes in AVM volume and quality of life, while watching for side effects. Because sirolimus is an immunosuppressant, this is a disease-control approach, not a cure.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ARTERIOVENOUS MALFORMATIONS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
APHM
NOT_YET_RECRUITINGMarseille, 13000, France
Contact
Contact Email: •••••@•••••
Contact
-
APHP
NOT_YET_RECRUITINGParis, 75000, France
-
CHRU Lille
NOT_YET_RECRUITINGLille, 59000, France
-
CHU Amiens
RECRUITINGAmiens, 80000, France
Contact
Contact
-
CHU Bordeaux
NOT_YET_RECRUITINGBordeaux, 33000, France
-
CHU Dijon
RECRUITINGDijon, 21000, France
Contact
Contact
-
CHU Montpellier
NOT_YET_RECRUITINGMontpellier, 34000, France
-
CHU Nancy
NOT_YET_RECRUITINGNancy, 54000, France
-
CHU Nice
NOT_YET_RECRUITINGNice, 06000, France
-
CHU Strasbourg
NOT_YET_RECRUITINGStrasbourg, 67000, France
-
CHU Tours
NOT_YET_RECRUITINGTours, 37000, France
-
HCL Lyon
RECRUITINGLyon, 69000, France
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
UCL
NOT_YET_RECRUITINGBrussels, Belgium
Conditions
Explore the condition pages connected to this study.