Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New study tracks pregnancy dangers in rare vascular conditions

NCT ID NCT04194619

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 400 pregnant women with rare blood vessel diseases (like HHT, Marfan syndrome, or lymphedema) to learn about serious pregnancy complications. Researchers will ask participants about their health during pregnancy and for 12 months after birth. The goal is to gather data to create better safety recommendations—no new treatments or medications are being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2020

Expected to finish

Nov 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study describes severe and specific obstetrical complications during and after pregnancy (until 12 months postpartum) for the following pathologies: heredity hemorrhagic telangiectasia, marfan syndrome or related, primary lower limb lymphedema, superficial arteriovenous malformations or even cerebro-spinal arteriovenous malformations.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged ≥ 18 years and ≤45 years at the time of inclusion * Pregnant and/or having given birth less than 1 month (≤ 30 days) * Clinically and/or radiological and/or molecular biology diagnosis of a rare vascular disease before or during pregnancy or one month after delivery. * Having been informed of all pertinent aspects of the study and provided oral non-opposition. Exclusion Criteria: * Any person not fulfilling the inclusion criteria or refusing to take part in the study. * Major under legal protection

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Arteriovenous malformations are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

arteriovenous hemangioma/malformation arteriovenous malformations of the brain central nervous system disorder hereditary hemorrhagic telangiectasia lymphedema Marfan and Marfan-related disorder Marfan syndrome primary lymphedema vascular malformation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arteriovenous malformations Cerebrospinal; disorder Lymphedema primary Marfan syndrome or related Osler rendu disease Vascular anomaly

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    32 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Dijon Bourgogne - Hôpital François Mitterrand

    RECRUITING

    Dijon, France

  • CHU de Marseille - Hôpital de la Timone

    RECRUITING

    Marseille, 13385, France

  • CHU de Nancy - Hôpitaux de Brabois

    WITHDRAWN

    Vandœuvre-lès-Nancy, 54511, France

  • CHU de Strasbourg, Hôpital de Hautepierre

    RECRUITING

    Strasbourg, 67200, France

  • Centre de Référence pour la maladie de Rendu-Osler - Service Génétique Clinique - Hôpital Femme-Mère-Enfant - Hospices Civils de Lyon

    RECRUITING

    Bron, 69677, France

  • Clinique cardiologique et des maladies vasculaires CHU de Nantes, Hôpital G. R. LAENNEC

    RECRUITING

    Saint-Herblain, 44800, France

  • Service Maladies vasculaires - HTA - NHC Pôle Médico-chirurgicale cardio-vasculaire, CHU de Strasbourg - Hôpital Civil

    RECRUITING

    Strasbourg, 67091, France

  • Service Médecine Interne - Hôpital Saint-Eloi, CHU de Montpellier

    RECRUITING

    Montpellier, 34295, France

  • Service Médecine Interne - Médecine vasculaire - CHU de Rouen, Hôpital Charles Nicolle

    WITHDRAWN

    Rouen, 76000, France

  • Service Médecine Interne Estaing CHU de Clermont-Ferrand - Hôpital d'Estaing

    RECRUITING

    Clermont-Ferrand, 63000, France

  • Service Médecine interne - CHRU de Lille - Hôpital Claude Huriez

    RECRUITING

    Lille, 59037, France

  • Service Pneumologie et Oncologie Thoracique - AP-HP Hôpital Ambroise Paré

    RECRUITING

    Boulogne-Billancourt, 92104, France

  • Service Pneumologie, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de TOURS

    RECRUITING

    Tours, 37044, France

  • Service Radiologie-pneumologie interventionnelle - Hôpital Tenon AP-HP

    RECRUITING

    Paris, France

  • Service d'Imagerie Pédiatrique et Fœtale et Consultation Pluridisciplinaire des Angiomes - Hôpital Femme-Mère-Enfant - HCL

    RECRUITING

    Bron, 69677, France

  • Service d'imagerie médicale - Neuroradiologie interventionnelle - Hôpital Neurologique P. Wertheimer - HCL

    WITHDRAWN

    Bron, 69677, France

  • Service de Cardiologie - Hôpital Bichat, AP-HP

    RECRUITING

    Paris, 75018, France

  • Service de Cardiologie _ Hôpital des Enfants (Purpan)

    RECRUITING

    Toulouse, 31026, France

  • Service de Génétique CHU de Poitiers

    RECRUITING

    Poitiers, 86021, France

  • Service de Génétique, Hôpital Femme-Mère-Enfant

    RECRUITING

    Bron, 69677, France

  • Service de Lymphologie - Hôpital Cognacq-Jay - Paris

    RECRUITING

    Paris, 75015, France

  • Service de Médecine Interne + Service Médecine Vasculaire _ Hôpital RANGUEIL

    RECRUITING

    Toulouse, 31059, France

  • Service de Médecine Interne et Maladies Vasculaires + Service Neuropédiatrie et neurochirurgie de l'enfant - CHU Angers

    RECRUITING

    Angers, 49933, France

  • Service de Médecine Interne-Médecine Vasculaire, CHU de Nantes - Hôtel Dieu

    RECRUITING

    Nantes, 44093, France

  • Service de Médecine Vasculaire - Hôpital de la Côte de Nacre

    RECRUITING

    Caen, 14033, France

  • Service de Médecine Vasculaire et Thérapeutique, Explorations Fonctionnelles Vasculaires - CHU de Saint-Etienne - Hôpital Nord

    RECRUITING

    Saint-Etienne, 42055, France

  • Service de Médecine interne et immunologie clinique + Service de Médecine Vasculaire - Hôpital Saint André, CHU de Bordeaux

    WITHDRAWN

    Bordeaux, 33075, France

  • Service de Médecine vasculaire et HTA - Hôpital Albert Calmette, CHRU de Lille

    RECRUITING

    Lille, 59037, France

  • Service de Neuroradiologie - AP-HP - Paris (Hôpital Lariboisière)

    RECRUITING

    Paris, 75010, France

  • Service de Neuroradiologie Interventionnelle - Fondation Adolphe de Rothschild

    RECRUITING

    Paris, 75019, France

  • Service de Neuroradiologie Interventionnelle - Hôpital Foch

    RECRUITING

    Suresnes, 92151, France

  • Service de Pneumologie CHU de Rennes - Hôpital Pontchaillou

    RECRUITING

    Rennes, 35033, France

  • Service de dermatologie, CHU de Nice - Hôpital l'Archet 2

    RECRUITING

    Nice, 06202, France

  • Service de neuroradiologie diagnostique et interventionnelle - CHU de Nancy, Hôpital St-Julien

    RECRUITING

    Nancy, 54035, France

  • Unité de Génétique médicale, CHU de Rennes, Hôpital Sud

    RECRUITING

    Rennes, 35203, France

  • Unité de neuro-interventionnelle CHU Nice, Hôpital Pasteur 2

    RECRUITING

    Nice, 06001, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.