Alexandria University
Clinical trials sponsored by Alexandria University, explained in plain language.
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New jaw plate could mean faster healing for broken jaws
Disease control CompletedThis study tested a new type of metal plate (modified 3D rectangular grid plate) to fix broken jaw bones in the front and side areas. Twenty-two adults with recent jaw fractures were treated with either the new plate or a standard miniplate. The researchers measured pain, how wid…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 26, 2026 05:11 UTC
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Which crown wins? study tests new materials for Kids' cavities
Disease control CompletedThis study tested three types of dental crowns (bioflex, zirconia, and stainless steel) for restoring badly decayed back baby teeth in 45 children aged 6 to 8. Researchers checked gum health, crown fit, surface smoothness, color, and how happy parents and kids were with the resul…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 26, 2026 05:07 UTC
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Fish oil and aspirin may boost gum treatment in smokers
Disease control CompletedThis study tested whether taking omega-3 supplements and low-dose aspirin, with or without an antibiotic, could improve standard gum treatment in smokers with advanced periodontitis. 45 smokers participated. The goal was to see if these additions helped reduce gum pocket depth an…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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Faster dental implants? new study tests early loading
Disease control CompletedThis study looked at whether dental implants with a special calcium titanate surface can be loaded (fitted with a crown) sooner than usual. 22 adults with good jawbone received implants in the lower back jaw. Researchers measured implant stability and bone changes over time to se…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Jaw fracture surgery: which approach is safer for nerves?
Disease control CompletedThis study compared two surgical techniques for fixing a broken lower jaw joint (subcondylar fracture). Twenty patients were randomly assigned to receive either a newer approach (transmasseteric anteroparotid) or a standard approach (retromandibular transparotid). The goal was to…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Olive oil and bee glue take on cavity bugs in kids
Disease control CompletedThis study tested three mouthwashes—ozonated olive oil, propolis (a bee product), and chlorhexidine—in 51 children at high risk for cavities. The goal was to see which one best reduced bacteria that cause tooth decay. Researchers measured bacterial counts and plaque buildup befor…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Plastic vs. titanium: which plate mends a broken jaw better?
Disease control CompletedThis study tested whether custom-made 3D-printed plastic (PEEK) plates work as well as standard titanium plates for fixing a specific type of jaw fracture. Eighteen adults with a broken jaw angle were randomly assigned to receive one of the two plate types. The researchers measur…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New flexible crowns tested for Children's teeth – are they as good as metal?
Disease control CompletedThis study tested a new type of tooth crown called BioFlex, made from a flexible material, against standard stainless steel crowns for cavities in children's back baby teeth. 74 children received one of each crown type using a gentle technique that doesn't require drilling or num…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New dental implant technique aims to save bone and gum contour
Disease control CompletedThis study tested a new method called vestibular socket therapy using a collagen membrane for immediate dental implants in people with a damaged front tooth. The goal was to see if it helps preserve the bone and gum shape better than the standard approach. Eighteen adults with a …
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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New study tests magnetic mallet vs piezotome for easier dental implants
Disease control CompletedThis study looked at 20 people with a narrow upper jawbone who needed dental implants. It compared two tools—a magnetic mallet and a piezotome—to widen the bone and place implants and bone graft at the same time. The goal was to see which tool gives better implant stability and l…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New 3D mesh could improve surgery for broken bones around the eye
Disease control CompletedThis study tested a new 3D-printed mesh for repairing complex fractures around the eye socket and cheekbone. Twenty-four adults with these fractures received either the new mesh or standard metal plates and screws. The goal was to see if the new mesh led to better bone alignment …
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New study tests better membranes for dental implants in weak jawbones
Disease control CompletedThis study tested two types of platelet-rich fibrin (PRF) membranes used with bone graft to support dental implants in people with a thin lower jaw. Twenty adults with missing back teeth and a narrow jawbone received implants along with either a standard PRF or an extended PRF me…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 04, 2026 16:17 UTC
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New jaw surgery shows promise for cleft patients
Disease control CompletedThis study tested a modified jaw surgery (Le Fort I osteotomy) in 9 adults with cleft lip and palate who also had a misaligned bite and a bone gap in the upper jaw. The surgery aimed to improve facial profile and close the bone gap. Researchers measured changes in the bone defect…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Sugar-Free wipes take aim at baby tooth decay
Prevention CompletedThis study tested whether cleaning babies' teeth and gums with special xylitol wipes three times a day for four weeks could reduce cavity-causing bacteria. Twenty healthy children aged 9 to 18 months took part. Researchers measured bacteria and acid levels in saliva weekly to see…
Phase: NA • Sponsor: Alexandria University • Aim: Prevention
Last updated May 26, 2026 05:07 UTC
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New nerve block eases back pain in disc disease study
Symptom relief CompletedThis study tested a nerve block called erector spinae plane block for chronic low back pain caused by degenerative disc disease. Forty adults aged 30 to 65 with moderate to severe pain that didn't improve with other treatments received the injection. The goal was to reduce pain a…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:14 UTC
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Laser or light: which fades scars better?
Symptom relief CompletedThis study tested two different light treatments to reduce redness in scars from injuries or surgery on the head and neck. Forty people with scars less than six months old received four sessions of either a long-pulsed ND:YAG laser or intense pulsed light. The goal was to see whi…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:14 UTC
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Insulin ointment speeds healing of blistering skin disease?
Symptom relief CompletedThis study tested whether applying insulin directly to skin sores helps them heal faster in people with pemphigus vulgaris, a rare autoimmune blistering disease. Twenty patients each had three similar sores treated with either long-acting insulin, short-acting insulin, or a saltw…
Phase: PHASE2 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:13 UTC
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Jaw pain relief: ozone and platelet therapy shows promise in small trial
Symptom relief CompletedThis study tested whether adding platelet-rich plasma (PRP) to ozonated water during a jaw joint washout procedure (arthrocentesis) helps people with a displaced jaw disc that causes pain and trouble opening the mouth. Twenty adults who did not get better with standard care took …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:11 UTC
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Antidote for Drug-Induced delirium shows promise in 100-Patient trial
Symptom relief CompletedThis study tested whether rivastigmine can safely reverse confusion and drowsiness caused by poisoning from certain drugs like antidepressants and antipsychotics. Researchers treated 100 patients at a poison center and measured changes in consciousness and agitation. The goal was…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:09 UTC
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Laser zaps pain after kids' tooth pulls
Symptom relief CompletedThis study tested whether a low-level laser can improve healing and reduce pain after removing baby molars in children aged 5 to 8. Each child had two teeth pulled; one side got laser treatment and the other did not. Pain and healing were checked on days 3 and 7 using questionnai…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:08 UTC
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Ketamine cocktail may ease infant surgery pain
Symptom relief CompletedThis study looked at whether adding ketamine to a standard numbing medicine (bupivacaine) helps control pain better in infants after open kidney surgery. Forty infants under 1 year old were split into two groups: one got the standard numbing block, the other got the numbing block…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:08 UTC
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Magnesium boosts pain relief after gastric sleeve surgery
Symptom relief CompletedThis study tested whether adding magnesium sulfate to a common painkiller (bupivacaine) could improve pain control after laparoscopic sleeve gastrectomy, a type of weight-loss surgery. 68 adults aged 18-50 with a BMI of 30-50 took part. The goal was to see if the combination woul…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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Virtual reality calms heart patients better than muscle relaxation?
Symptom relief CompletedThis study tested two simple, drug-free methods to help heart patients in the cardiac care unit feel less anxious and more focused. One group used virtual reality (VR) headsets, while the other group practiced a modified muscle relaxation technique. The goal was to see which meth…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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Licorice or laser: which fades dark gums better?
Symptom relief CompletedThis study tested two treatments for dark gums (gingival pigmentation) in 26 healthy adults. One group received a diode laser treatment, the other a licorice extract gel applied to the gums. Researchers measured changes in pigmentation and patient satisfaction over 36 weeks to se…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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Tea tree oil vs. standard burn care: which heals better?
Symptom relief CompletedThis study tested whether dressings soaked in tea tree oil help second-degree burns heal better than standard dressings. Thirty patients with fresh burns covering up to 10% of their body took part. Researchers checked wound appearance and signs of infection over 10 days. The goal…
Phase: EARLY_PHASE1 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 04:38 UTC
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Gadgets vs. dental pain: tech distractions help kids with ADHD
Symptom relief CompletedThis study tested whether technology-based distractions (like videos or games) can reduce pain and anxiety in 48 children with ADHD during dental procedures. All children were on stimulant medication and had no prior dental experience. Researchers measured pain through behavior, …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 26, 2026 04:35 UTC
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Ozonated gel or TPRF: which heals palate wounds better?
Symptom relief CompletedThis study tested two treatments—ozonated gel and titanium platelet-rich fibrin (TPRF)—to help heal wounds on the palate after gum graft surgery. 39 people with gum recession took part. The goal was to see which treatment reduced pain and shrunk the wound faster. Results can help…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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New pump technique for TMJ pain shows promise in small trial
Symptom relief CompletedThis study tested a new way to wash out the jaw joint (arthrocentesis) using a dental implant motor pump to create higher pressure, compared to the usual method. Thirty adults with a common TMJ disorder that causes pain and clicking took part. The goal was to see if the new pump …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Laser wisdom tooth removal may reduce pain and swelling
Symptom relief CompletedThis study tested whether using an Er:YAG laser to remove impacted wisdom teeth is better than the usual surgical method. Twenty-four healthy adults aged 20-30 took part. The researchers measured pain, swelling, and how well the mouth could open after surgery to see if the laser …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Ozone shots for jaw pain? small study tests different strengths
Symptom relief CompletedThis study tested different strengths of ozone gas injections into the jaw joint to treat pain, clicking, and limited mouth opening. Twenty adults who had not improved with other treatments received the injections. The goal was to see if ozone could ease symptoms and improve jaw …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Which pain block works best for kids? new study compares two techniques
Symptom relief CompletedThis study looked at 60 children aged 2 to 7 having lower abdominal surgery. It compared two ways to manage pain: an erector spinae block and a caudal block. The goal was to see which method provides better pain relief during and after surgery, using a standard pain scale.
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Tailored tools make jaw surgery more precise
Symptom relief CompletedThis study tested whether custom-made surgical stents and plates could help doctors fix broken jaw bones more accurately. Seven patients with a specific type of jaw fracture received the personalized tools during surgery. The goal was to see if the guides improved bone alignment …
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New pain block combo eases drain discomfort after heart surgery
Symptom relief CompletedThis study tested whether adding two extra nerve blocks to a standard one can better control pain from chest drains after heart surgery. 180 adults having planned heart surgery through the breastbone took part. The goal was to see if these extra blocks reduce pain at the drain si…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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AI training boosts nurse ECG skills in new study
Knowledge-focused CompletedThis study tested a new training program that uses artificial intelligence to create realistic heart test scenarios for nurses. 64 nurses participated to see if the training improved their knowledge, decision-making, and confidence in reading ECGs. The goal was to improve educati…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:16 UTC
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3D printed guides promise precision in jaw fracture repair
Knowledge-focused CompletedThis study tested how accurately 3D printed surgical guides help repair broken jawbones. Twenty-four patients with a single-sided jaw fracture received surgery using one of two virtual planning methods. The goal was to see which method produced a more precise bone alignment after…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:16 UTC
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Green dialysis: less fluid, same results?
Knowledge-focused CompletedThis study looked at whether using a lower dialysate flow rate during hemodialysis can still clean the blood effectively while helping patients recover faster and feel better. 80 adults with end-stage kidney disease each tried both high and low flow settings for a week. The goal …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:15 UTC
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Gum disease hormone clue in obese patients explored
Knowledge-focused CompletedThis study looked at levels of a hormone called prolactin in the gum fluid of 26 obese people with and without gum disease (periodontitis). Researchers measured prolactin before and after non-surgical gum treatment to see if it changed. The goal was to better understand the link …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:14 UTC
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Vaping lung damage: new study reveals best diagnostic tools
Knowledge-focused CompletedThis study looked at 60 adults with breathing problems linked to vaping. Doctors used chest CT scans, ultrasound, and a procedure called bronchoalveolar lavage (BAL) to check for lung injury. The goal was to see how well these tests work together to diagnose the condition and pre…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:12 UTC
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Which side is better for a safer central line? new study investigates
Knowledge-focused CompletedThis study looked at 80 patients who needed a port-a-cath (a small device for long-term medicine delivery). Doctors used ultrasound to guide a tube into a large vein under the collarbone, comparing the right and left sides. The goal was to see which side leads to more successful …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:11 UTC
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ER study reveals widespread hidden painkiller habit
Knowledge-focused CompletedThis study checked how many people coming to the emergency room regularly use NSAID painkillers (like ibuprofen or naproxen). Researchers surveyed 350 adult patients at Alexandria Main University Hospital. They also asked if patients knew about the side effects of long-term use. …
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:10 UTC
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Digital dentistry showdown: which bracket bonding method wins?
Knowledge-focused CompletedThis study tested two different digital techniques for placing braces brackets to see which one is more accurate. Eighteen people with mild to moderate crowding got brackets on both sides of their mouth using a different method on each side. The goal was to measure how close the …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:10 UTC
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Researchers hunt for clues to who benefits from back pain injections
Knowledge-focused CompletedThis study looked at 100 adults with sacroiliac joint pain to find out which patient traits predict better results from a steroid injection. Researchers measured pain and disability before and after the injection. The goal was to help doctors choose the right patients for this tr…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:08 UTC
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Tiny bone punctures may boost jaw widening in adults, study finds
Knowledge-focused CompletedThis study looked at 24 adults with a narrow upper jaw to see if adding small bone punctures (corticopunctures) to a miniscrew-assisted expander helps widen the jaw better than the expander alone. The goal was to measure changes in the jaw bone and teeth position using 3D scans. …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:07 UTC
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Sleep apnea may raise risk of repeat blood clots, study suggests
Knowledge-focused CompletedThis study looked at 40 adults who had a pulmonary embolism (a blood clot in the lung) to see if those with sleep-disordered breathing had worse short-term outcomes or a higher chance of another clot within one year. Researchers compared patients with and without sleep apnea usin…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:06 UTC
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Fast-Track hip surgery may cut death risk, study finds
Knowledge-focused CompletedThis study looked at whether fixing a hip fracture within 48 hours reduces the chance of death and other problems. Researchers followed 150 adults aged 50 and older who had hip surgery at Alexandria University Hospitals. They measured deaths within 30 days, blood clots, confusion…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 05:06 UTC
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AI tutors boost student thinking and empathy in clinical training
Knowledge-focused CompletedThis study tested whether AI-powered learning platforms could improve reflective thinking, emotional competence, and clinical skills in nursing students. 140 students from Alexandria University took part. Researchers measured changes in how students think about their actions, han…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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Pharmacists on the ICU team cut medication errors in hospital transfers
Knowledge-focused CompletedThis study tested whether having a clinical pharmacist review medications when patients are moved to the intensive care unit (ICU) reduces errors. The researchers compared prescriptions checked by pharmacists versus those checked by ICU doctors alone. They included 126 patients t…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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New program teaches teens to say no to drugs
Knowledge-focused CompletedThis study tested a special educational program designed to improve teenagers' knowledge and behavior around substance abuse. The program was based on the Behavior Change Wheel model. A total of 226 adolescents aged 10 to 18 took part. The goal was to see if the program could hel…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Sarcoidosis drugs under scrutiny: do they trigger lymphoma?
Knowledge-focused CompletedThis study followed 40 adults with sarcoidosis who were taking immunosuppressive therapy to see if they developed lymphoma within a year. Researchers checked for lymphoma through lymph node biopsies. The goal was to understand whether these drugs increase cancer risk.
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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AI boosts nurse drug skills in new study
Knowledge-focused CompletedThis study tested whether an AI-powered app could improve nurses' ability to calculate medication doses compared to standard classroom training. 56 nurses from various hospital units took part. The goal was to see if the app leads to better knowledge, decision-making, and confide…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Distracted by devices: 105 patient safety incidents linked to nurse smartphone use
Knowledge-focused CompletedThis study looked at how nurses use smartphones during work and whether it impacts patient safety. Researchers surveyed 368 nurses in Egypt and found 105 clinical incidents linked to smartphone distraction. The goal was to understand the risks and gather nurses' ideas for safer u…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Computer-Aided jaw surgery shows promise in small trial
Knowledge-focused CompletedThis study tested whether using computer planning and custom-made plates could improve jaw bone reconstruction after tumor surgery. Thirty people with non-cancerous jaw tumors took part. The approach aimed to make surgery more accurate and improve healing and appearance. Results …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC