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Custom 3D-Printed plates and rib grafts show promise for jaw reconstruction

NCT ID NCT07551154

Disease control Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to rebuild the lower jaw after removing benign tumors. Surgeons used virtual 3D planning to create custom-made plates and combined them with a piece of the patient's own rib bone. Thirty people took part, and the team checked how well the wounds healed, how the jaw looked afterward, and how satisfied patients were.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
custom-made plate and split rib bone graft
What this could lead to
If successful, this approach could make jaw reconstruction more precise and improve healing and appearance for patients after tumor surgery.
What could go wrong
This is a small, completed study with only 30 participants, so results may not apply to everyone. Custom implants are also more expensive and not widely available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Benign mandibular tumors planned to be managed by segmental mandibulectomy. * Adequate soft tissue coverage after mandibular resection. Exclusion Criteria: * Patients not suitable for general anesthesia because of severe systemic medical problems, * Soft Tissue deficiency after resection, which are better treated by free osseo-cutaneous flaps. * Planning to have postoperative radiotherapy or with history of head and neck radiotherapy. * Obvious preoperative infections at the site of surgical resection. * Recurrent lesions where wider resection will necessitate free composite flap reconstruction

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Conditions

The condition(s) this trial relates to.

benign neoplasm of lower jaw bone Mandibular Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mandibular injuries

Contacts and locations

Locations

  • Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt

    Alexandria, Azarita, 00203, Egypt