HEALTHY PARTICIPANTS

This early-stage study tested a single dose of a new drug called IBI3002 in 52 healthy volunteers and people with mild-to-moderate asthma. The main goal was to see if the drug is safe and how the body processes it. Researchers measured side effects and drug levels in the blood ov…

This study looked at whether a 12-week exercise program (three times a week) could improve thinking skills in healthy adults aged 50 to 80. Researchers measured changes in memory, attention, and related hormones like leptin and irisin. The goal was to understand how exercise migh…

This study tested a new version of the propellant used in salbutamol inhalers (a common asthma rescue medication) to see if it delivers the drug similarly to the current propellant. Sixty healthy adults aged 18 to 55 received single doses of salbutamol via both inhaler types. The…

This study looked at how a high-fat, high-calorie meal changes the amount of two drugs (zibotentan and dapagliflozin) in the blood of 26 healthy adults. Participants took a single dose of the combined pill either after eating or on an empty stomach. The goal was to understand foo…

This early-stage study aims to compare how two different pill versions of an experimental drug called LY4064809 are absorbed and processed by the body. It involves 24 healthy adult participants who will stay in a research center for about one month. The main goal is to measure ho…

This study looked at how a long-acting painkiller (nalbuphine ER) affects and is affected by two lung fibrosis drugs (pirfenidone and nintedanib) in 132 healthy adults. Researchers measured drug levels in the blood and checked for side effects. The goal was to gather safety and i…

This early-stage study tested a new drug called AZD8965 in 147 healthy volunteers to see if it is safe and how the body processes it. Some participants received the drug, others a placebo. The study also checked if food changes how the drug works. The goal was to gather basic saf…

This study looked at whether a 4-week program of elastic band exercises could improve hip strength and agility in 21 healthy young male basketball players aged 15-18. One group did the band exercises plus their regular training, while the other group only did regular training. Th…

This study looked at how breathing simulated wildfire smoke for one hour affects a blood marker called p-tau, which is linked to cognitive decline. Twelve healthy adults aged 18–40 had two visits: one with clean air and one with wildfire smoke. Blood tests and memory tasks were d…

This study looked at how a single session of resistance exercise, with or without extra stretching, affects blood vessels and blood pressure in healthy adults. 27 healthy men took part, and their blood vessel function and blood pressure were measured before, right after, and 30 m…

This study tested whether two different injection devices (a prefilled syringe and an autoinjector) deliver the same amount of the drug tozorakimab into the body. It involved 254 healthy volunteers who received a single dose under the skin. The goal was to see if the devices work…

This study tested the safety and tolerability of a new drug called LY4060874 in 121 healthy people. Participants were monitored for side effects and how the drug moves through the body. The study is complete and does not aim to treat any disease.

This study looked at how different amounts of water and delays before breakfast affect levels of a new semaglutide tablet in the blood. 121 healthy men took the tablet daily for 10 days, with varying water volumes (50 or 120 mL) and meal delays (30, 60, or 120 minutes). The goal …

This study looked at how the experimental prostate cancer drug opevesostat moves through the body in men with moderate liver impairment compared to healthy men. Sixteen male participants received a single dose, and researchers measured drug levels over time. The goal was to under…

This study tested how quickly Staccato alprazolam (an inhaled sedative) starts working compared to two other sedatives given through a vein or nose. Fifty-five healthy adults received single doses of each drug, and their brain activity was measured using an EEG. The goal was to s…

This study tested a single dose of the drug AZD4144 in 41 adults to see how their bodies processed it. Participants included people with severe kidney disease, those with end-stage kidney disease, and healthy volunteers. The goal was to understand the drug's safety and how it beh…

This study looked at how different types of stationary bike workouts affect muscle strength and overall fitness in 45 sedentary but healthy adults. Participants did either eccentric (resisting the pedal) or concentric (normal pedaling) cycling for 14 weeks. The goal was to see wh…

This study looked at how an experimental drug called AZD0780 changes the way the body processes metformin, a common diabetes medicine. Fourteen healthy volunteers took both drugs, and researchers measured drug levels and checked for side effects. The goal was to gather safety and…

This study looked at how two different forms of an experimental drug are absorbed by the body. It involved 18 healthy Chinese adults who took each version once under fasting conditions. The goal was to compare the drug levels in the blood, not to treat any disease.

This study looked at how a drug called vimseltinib affects the way the body handles metformin, a common diabetes medicine. Twenty-two healthy men took part to measure drug levels and check for side effects. The goal was to gather safety information, not to treat any disease.

This study looks at how a new drug called camizestrant affects the breakdown of other drugs in the body, and vice versa. It involves 40 healthy postmenopausal women who will take camizestrant along with midazolam or carbamazepine. The goal is to understand drug interactions, not …

This study looked at how much of the drug rozanolixizumab ends up in the breast milk of healthy women who are breastfeeding. Fifteen women who had already decided to stop breastfeeding received one dose of the drug, and their milk was tested over a week. The goal was to understan…

This early-stage study tested the safety and how the body processes a single dose of donzakimig in 32 healthy Chinese and Japanese adults. Participants received either the drug or a placebo, and researchers monitored for side effects and measured drug levels in the blood. The goa…

This study looked at how taking the drug Admilparant with or without food changes its levels in the body. Fifty-six healthy adults took the drug under different conditions. The results will help doctors know whether to take this medication with meals.

This study looked at how a new drug called elenestinib affects the way the body processes midazolam (a sedative) and a common birth control pill. Twenty healthy adult women took these medicines with and without elenestinib, and had blood tests to measure drug levels. The goal was…

This study looked at how the drug MK-5684 is processed in men with severe kidney failure or end-stage kidney disease compared to healthy men. Twenty-four men took a single dose, and researchers measured drug levels in the blood over time. The goal was to understand how kidney pro…

This study tested whether immersive virtual reality can affect memory, pain perception, and anxiety in healthy adults. Sixteen participants from a university psychology course completed word recall tests while using VR. The goal was to see if VR could distract people enough to re…

This study tested how safe and tolerable a subcutaneous (under the skin) injection of immunoglobulin G (a type of antibody) is in 82 healthy adults. Participants received the injection under different conditions to see how much pain or discomfort it caused. The goal was to gather…

This early-stage study tested the safety and how the body handles a new drug called AZD6793 in 39 healthy Japanese and Chinese adults. Participants received either the drug or a placebo, and researchers monitored for side effects and drug levels in the blood. The study was not de…

This study looked at whether a roller massage could temporarily lower blood pressure in healthy young adults. 29 people took part, and researchers measured changes in blood pressure and tissue hardness after the massage. The goal was to understand how massage might affect the bod…

This early-stage study tested a new drug called ATX101 in 24 healthy adults to see if it is safe and how the body processes it. Participants received a single dose of the drug through a vein. The goal was to check for side effects and measure drug levels in the blood, not to trea…

This study looked at whether a 5-day course of an oral NAD+ supplement changes key biological markers in healthy adults aged 45 to 75. Researchers measured NAD+ levels in blood cells and tracked safety through lab tests and daily symptom reports. The goal was to understand how th…

This study tested how well different versions of the drug TEV-56286 are absorbed by the body. 47 healthy adults took single doses of new and reference formulations. The goal was to compare absorption levels and check for safety. Participants were involved for about 70 days, inclu…

This study looked at how vimseltinib changes the way the body handles rosuvastatin, a cholesterol-lowering drug. Twenty healthy men took part to measure drug levels and check for side effects. The goal was to understand drug interactions, not to treat any disease.

This study looked at how a short, painless brain stimulation technique called continuous theta burst stimulation (cTBS) changes the way healthy young adults pay attention to emotional pictures, like a crying child or a smiling baby. 91 volunteers received either real or fake stim…

This study tested whether stretching or self-massaging the neck can improve flexibility in both the neck and the hip on the same side of the body. Thirty healthy adults each tried both techniques in random order. Researchers measured range of motion and tissue stiffness before an…

This study looked at whether a nature-based therapy program could help healthy adults in Barcelona feel better and handle stress. One hundred adults took part, and researchers measured their quality of life, stress levels, and emotions. The goal was to gather information to desig…

This study tested whether a new drug called CHS-1420 works similarly to the approved drug Humira in the body. It involved 238 healthy Chinese adults who received a single injection of either drug. The goal was to measure how the drug moves through the body, not to treat any disea…

This study looked at how three common drugs (an antifungal, an antibiotic, and acid reducers) change the levels of a new medicine called INCB161734 in the blood. 63 healthy adults aged 18-55 took part. The goal was to gather safety and drug interaction information, not to treat a…

This early-stage study tested the safety and how the body processes an inhaled drug called AZD4604 in 56 healthy Japanese and Chinese adults. Participants received either the drug or a placebo as single or multiple doses. The goal was to check for side effects and measure drug le…

This early-stage study tested a new medicine called PF-06414300 in 63 healthy adults to see how safe it is and how the body processes it. Participants received either the drug or a placebo and stayed at the clinic for monitoring. The goal was to gather safety data, not to treat a…

This study looked at how casdatifan, an experimental drug, interacts with two other medicines in 14 healthy adults. Participants took casdatifan alone and then with itraconazole (a strong CYP3A4 inhibitor) or phenytoin (a strong CYP3A4 inducer). The goal was to measure how these …

This study looked at how healthy adults absorb a drug called ZN-A-1041 when given as tablets versus capsules. 18 volunteers took part to help researchers understand which form works best. The study did not treat any disease and is already finished.

This study looked at how a single dose of the drug INCB099280 is absorbed, broken down, and removed from the body. Five healthy men took one pill, and researchers measured the drug and its byproducts in their blood, urine, and stool. The goal was to understand the drug's journey,…

This study looked at how a new insulin drug, THDB0206, works when injected into different body areas like the belly, arm, or thigh. It involved 27 healthy Chinese adults who each received a single dose at three different sites on separate days. The goal was to see how the injecti…

This study looked at how carrying a backpack on one or both shoulders changes the pressure on the soles of the feet in 92 healthy adolescents. Researchers found that carrying a backpack on one shoulder increased the foot's contact with the ground, but the overall pressure intensi…