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Drug interaction study: does capivasertib alter cholesterol med levels?

NCT ID NCT07088913

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 42 times

Summary

This completed Phase 1 study in 20 healthy adults tested whether taking capivasertib changes how the body absorbs and clears rosuvastatin, a common cholesterol-lowering drug. Participants received rosuvastatin alone and then again with capivasertib, and researchers measured drug levels in the blood. The goal is to understand potential drug interactions, not to treat any disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Baltimore, Maryland, 21225, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

capivasertib and rosuvastatin

What this could lead to

If successful, this could help doctors understand whether capivasertib changes how other drugs work in the body, leading to safer dosing guidelines.

What could go wrong

This is a very early, small study in healthy people, not patients. It only looks at drug levels in the blood, not real-world treatment outcomes or side effects.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.