Healthy volunteers help test how a new drug enters the blood
NCT ID NCT07339735
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how two different versions of the drug LY4064809 enter the bloodstream and how long the body takes to remove them. It involved 24 healthy adults who stayed at a research center for about a month. The goal was to gather information, not to treat any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
-
24 people
The number who actually took part.
- Started
-
Jan 2026
- Finished
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Mar 2026
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 55 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Are healthy as determined by medical evaluation, including medical history, physical examination, vital signs, and electrocardiogram (ECG) at screening and admission. * Have clinical laboratory test results within the normal range * Have normal blood pressure and pulse rate or not clinically significant * Have a BMI within the range 18 to 32 kg/m2 * Participants assigned male at birth or assigned female at birth who are not of childbearing potential Exclusion Criteria: * History or presence of any of the following conditions, deemed clinically significant by the investigator (or designee): * metabolic disease, including congenital non-hemolytic hyperbilirubinemia, for example, Gilbert syndrome * bile duct disease, including removal of the gall bladder * digestive system disease * blood disease * disease of the nervous system * significant history of, or presence of, liver disease, including any abnormal liver function tests * heart disease * Have an abnormal electrocardiogram (ECG) at screening or admission * History of a major surgical procedure within 30 days prior to screening * Diagnosed or treated cancer within 5 years prior to screening, with the exception of the following cancers cured through treatment: basal cell carcinoma of the skin, squamous cell carcinoma of the skin, and in situ carcinoma of the cervix cured through surgery * Clinically significant history of multiple or severe drug hypersensitivity reactions or drug allergies, as determined by the investigator * Have used or plan to use medication within 14 days prior to admission, or plan to use during the study with the exception of acetaminophen * Have creatinine lab clearance less than 90mL/min calculated using the Cockroft-Gault equation at screening * Have a positive Hepatitis B surface antigen (HBsAg), hepatitis C virus antibody or human immunodeficiency virus 1 and 2 antibody results at the screening visit
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fortrea Clinical Research Unit Inc. - Madison
Madison, Wisconsin, 53704-2526, United States
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