HEALTHY PARTICIPANTS

This early-stage study tests a new vaccine called VXB-251 in 240 healthy adults aged 60-83. The vaccine is designed to protect against three viruses that can cause serious lung infections: RSV, hMPV, and PIV3. Researchers are checking if the vaccine is safe and how well it trigge…

This study tests whether giving a high-dose flu vaccine together with a new long-acting antiviral drug (CD388) is safe and does not weaken the body's immune response. About 100 healthy adults aged 18 to 49 will receive either the vaccine plus CD388 or the vaccine plus a placebo. …

This study tests a new surgical approach (gingivalstat) against standard crown lengthening for people with a gummy smile caused by altered passive eruption. The goal is to see which method keeps the gum line more stable and looks better over 6 months. Twenty-two healthy adults ag…

This study tests whether a new biosimilar drug, CT-P52, works like the approved drug Taltz in healthy adults. About 218 participants aged 19 to 55 will receive a single dose of either CT-P52 or Taltz. Researchers will compare how the drug moves through the body and check for side…

This study looks at whether doing very short, intense bike sprints (just 10-20 seconds each, twice a week) can improve heart and lung fitness in inactive adults. Sixty healthy but inactive participants will be compared to a non-exercising group over 9 weeks. The goal is to see if…

This study looks at how well three different tablet versions of the drug LY4100511 are absorbed by the body in 48 healthy adults. It also checks if taking a common stomach acid medication (a proton pump inhibitor) changes absorption. The goal is to find the best tablet form for f…

This early-stage study tests whether a single dose of AG-236 is safe and tolerable in 24 healthy adults aged 18 to 55. Participants receive either the drug or a placebo by injection. The goal is to gather safety information and measure how the drug moves through the body, not to …

This early-stage trial tests the safety and tolerability of a new drug, STAR-0310, in 40 healthy adults. Participants receive a single dose (either the drug or a placebo) and are monitored for side effects, how the drug moves through the body, and immune reactions. The goal is to…

This early-stage study tests the safety and how the body handles a new drug, AZD0292, in 18 healthy Japanese adults. Participants receive a single dose of the drug or a placebo by IV. The main goal is to check for side effects and measure drug levels in the blood.

This study looks at whether a special breathing warm-up can make athletes' breathing muscles stronger during exercise. Researchers will compare a real breathing warm-up, a fake one, and no warm-up at all in 28 trained athletes aged 14 to 30. The goal is to see how long any streng…

This study tests whether using a simple pillow can teach CPR as effectively as a standard manikin. About 128 healthy adults over 18 will learn CPR using either a pillow or a manikin. Researchers will measure compression count, depth, and hand position to see if pillows are a good…

This study looks at how a new medicine, AZD4144, moves through and leaves the body. Eight healthy men aged 30-65 will receive a single dose either by mouth or injection. The drug is labeled with a tiny amount of carbon-14 so researchers can track it in blood, urine, and stool. Th…

This study looks at whether focused ultrasound can alter the effects of propofol, a common anesthesia drug. Ten healthy adults will receive both real and fake ultrasound during sedation. Researchers will measure brain signals and responses to commands to understand how ultrasound…

This study tests a new medicine called QL2106 against an approved drug, Tremfye, in 190 healthy adults aged 18-45. The goal is to see how the body processes each drug, check for side effects, and measure immune responses after a single dose. Participants must be in good health an…

This study looks at brain activity and heart rhythms in 45 people—some who have had a stroke and some who are healthy. Using special head sensors and heart monitors, researchers measure how the brain's front part works and how the heart beats during rest. The goal is to find diff…

This study looks at whether listening to self-chosen Levantine music can change how healthy young adults feel pain and emotions. Thirty-two participants will have their pain threshold tested after silence and after music. The goal is to see if music can be a simple, drug-free way…