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Obesity drug AZD4144 shows early safety signals in small trial

NCT ID NCT06942923

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 32 times

Summary

This early-stage study tested a daily pill called AZD4144 in 28 people with obesity to see if it is safe and how it affects inflammation in the body. Participants took either the drug or a placebo for a short time. The main goals were to check for side effects and measure changes in blood markers like interleukin-6 (IL-6), which is linked to inflammation.

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Contacts and locations

Locations

  • Research Site

    Berlin, 14050, Germany

Conditions

The condition(s) this trial relates to.

atherosclerosis chronic renal failure syndrome Obesity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.