CARDIAC SURGERY

This study tested whether frozen platelets can control bleeding as well as standard fresh platelets in 161 adults undergoing heart surgery with a heart-lung machine. The goal was to see if the frozen version is a safe and effective alternative. Results will help determine if froz…

This study tested whether giving vitamin E (alpha-tocopherol) during heart surgery reduces damage to the heart muscle in children with Tetralogy of Fallot, a birth defect. 60 children aged 1-10 years received either vitamin E or a placebo at the start of surgery. The main goal wa…

This study looked at whether using half the usual dose of heparin during heart surgery (bypass or valve replacement) could reduce bleeding afterward. 238 adults took part. The goal was to see if a lower dose is safer without increasing other risks.

This study looked at whether drinking a carbohydrate-rich beverage two hours before heart surgery could reduce insulin resistance—a condition where the body struggles to manage blood sugar, which can slow recovery. Fifty adults undergoing heart surgery with a bypass machine were …

This study looked at whether giving the drug ulinastatin during heart surgery can lower the chance of lung complications like infection or breathing trouble. Researchers reviewed records from over 4500 adults having heart surgery and also did lab tests to understand how the drug …

This study tested whether the anesthesia drug sevoflurane protects the heart more than propofol during planned aortic valve replacement. Researchers measured a heart stress marker (troponin) in 82 adults undergoing surgery. The goal was to see if combining sevoflurane before and …

This study tested whether dexmedetomidine, a sedative that preserves breathing better than other drugs, can protect the heart during cardiac bypass surgery. Researchers measured heart damage in 224 adults undergoing heart surgery with a heart-lung machine. The goal was to see if …

This study tested a new way to decide when to give blood transfusions during heart surgery. Instead of using a fixed hemoglobin level, doctors used a measure of oxygen in the blood (SvO2) to guide transfusions. The goal was to see if this approach could safely reduce the number o…

This study looked at 60 obese patients having heart surgery with a heart-lung machine. It compared two ways of giving the blood thinner heparin: one based on actual body weight and one based on ideal body weight. The goal was to see if using ideal body weight could prevent too mu…

This study tested if being in a room with natural light instead of artificial light can help prevent delirium (sudden confusion) after heart surgery. Researchers observed 448 adults who had planned heart surgery and needed intensive care. They compared how many people became conf…

This study tested a low-dose drug called landiolol to prevent atrial fibrillation (a type of irregular heartbeat) after heart surgery. About 400 non-Asian adults who had heart surgery took part. The goal was to see if landiolol could lower the chance of developing this complicati…

This study looked at whether special nerve blocks (fascial plane blocks) could improve pain control and breathing after open-heart surgery. 206 adults having heart surgery were split into two groups: one got the nerve blocks plus standard care, the other got standard care alone. …

This study looked at whether giving the sedative dexmedetomidine during open-heart surgery helps protect brain function afterward. Researchers measured thinking skills and a blood marker of nerve damage in 32 adults. The goal was to see if the drug could reduce confusion or memor…

This study tested whether giving methadone as a pill before heart surgery works as well as giving it through an IV during surgery for controlling pain afterward. 41 adults having planned heart surgery took part. Researchers measured how much extra pain medicine they needed and th…

This study tested whether giving the drug ketamine during heart surgery can lower the body's inflammatory response, which is linked to complications. 177 adults having planned heart surgery were randomly assigned to receive ketamine or standard anesthesia. Researchers measured bl…

This study tested whether giving a low dose of dexmedetomidine at night can prevent delirium (sudden confusion) in older adults after heart surgery. About 500 patients aged 60-89 were enrolled. The drug aims to improve sleep and reduce brain complications, potentially improving s…

This study tested whether a 20-minute nurse-led session of relaxation, breathing, and culturally appropriate prayer could help heart surgery patients stay calm and physically stable before their operation. 248 adults in Indonesia took part. The goal was to see if this approach co…

This study tested two methods of numbing the chest after heart surgery to see which one works better for pain control. 72 adults were randomly assigned to get either one nerve block or a combination of two blocks. The goal was to find out if the combined approach reduces pain, cu…

This study tested a simple, non-invasive technique to numb the airway before giving anesthesia for heart surgery. The goal was to see if it could prevent dangerous drops in blood pressure and reduce the need for strong painkillers. The study involved 106 adults having planned hea…

This study tested a program that combines counseling (behavioral activation) with medication adjustments to reduce depression and anxiety in older adults (age 60+) having heart surgery. 105 participants were split into two groups: one received the program, the other got usual car…

This study looked at whether giving a single dose of esketamine, a drug related to ketamine, could help reduce anxiety and depression in people having heart valve surgery. 142 adults took part, and researchers measured their mood before and after surgery using standard questionna…

This study tested two types of nerve blocks (ESP and SAP) to manage pain after heart surgery done through a small chest cut. 57 adults took part to see which method better reduces the need for strong painkillers and improves recovery. The goal is to find a safer, more effective w…

This study looked at how two different heart protection solutions affect the heart muscle during bypass surgery. Researchers measured amino acid levels and injury markers in 20 patients. The goal was to understand which method might better protect the heart during surgery.

This study looked at whether having too much or too little oxygen after heart surgery raises the chance of delirium (sudden confusion). Researchers followed 1000 patients in the ICU after cardiac surgery. The goal was to understand how oxygen levels impact recovery and brain func…

This study looked at 600 heart surgery patients to see if a new, rapid blood test called Quantra can accurately measure bleeding risk. The goal was to find out if Quantra could replace or support standard lab tests to help doctors decide when to give blood transfusions. The study…

This study looked at whether giving extra oxygen during heart-lung bypass affects kidney function after heart surgery. 104 adults having planned heart surgery took part. The goal was to see if extra oxygen helps or harms the kidneys and other organs.

This study tested whether a simple electronic wristband could help doctors understand how well patients recover after heart surgery. 137 adults wore the wristband for two months after leaving the hospital, and it counted their daily steps. The goal was to see if step counts could…

This study looked at over 13,000 adults who had heart surgery to understand how receiving a blood transfusion during the operation affects the link between having low red blood cells (anemia) before surgery and developing complications afterward. The goal was to see if the transf…

This study looked at a type of cell stress called endoplasmic reticulum stress in 53 adults having heart surgery with a heart-lung machine. Researchers took blood samples before and after the machine was used to measure changes in stress markers. The goal was to better understand…

This study observed 147 heart patients who had a stent placed and were taking two blood thinners (dual antiplatelet therapy) when they needed surgery. The goal was to see how doctors currently handle these medications before, during, and after surgery, and to track rates of bleed…

This study tested a way to give anesthesia during heart surgery using much less gas than usual. The goal was to see if it safely reduces medicine use and pollution. 92 adults having planned heart surgery took part. Researchers measured how much anesthesia was used and estimated t…

This study looked at 84 adults who had open-heart surgery through a chest incision (sternotomy). Researchers used a pain-mapping tool called algocartography two days after surgery to measure the area of increased sensitivity around the scar. They then checked if that area could p…

This study looked at whether using a noninvasive monitor called the Pleth Variability Index (PVI) helps doctors give the right amount of fluid during heart surgery. The goal was to reduce blood loss and the need for blood transfusions. 80 adults having heart surgery took part. Th…

This study looked at whether two types of heart ultrasound—one done on the chest and one done through the throat—give the same measurements of right heart function during heart surgery. 90 adults having scheduled heart surgery took part. The goal was to see if these methods can b…

This study looked at 40 adults having heart surgery with a heart-lung machine. The goal was to measure how fast pulse waves travel from the heart to different parts of the body. This helps doctors understand why blood pressure readings can differ between the arm and the leg durin…

This study looked at 455 adults who had heart surgery with a heart-lung machine. Researchers checked if routine blood tests and kidney function before surgery could predict acute kidney injury afterward. The goal is to help doctors identify high-risk patients earlier.

This study tested whether a breathing test can help doctors predict if heart surgery patients need more fluids. 90 adults on breathing machines were observed after surgery. The goal was to see if the test could prevent fluid overload, a common complication.

This study looked at 160 adults who had heart surgery to see if using a measure of oxygen in the blood (ScvO2) could lead to better decisions about when to give a blood transfusion, compared to the usual method of using a fixed hemoglobin level. The goal was to see if this approa…

This study reviewed medical records of 901 infants who had surgery for aortic coarctation (a narrowed heart artery) before age one. Researchers wanted to find out how many later developed high blood pressure or re-narrowing of the artery. The goal is to better understand these lo…

This study looked at 38 adults having heart surgery to better understand how the heart muscle gets injured during the procedure. Researchers used cardiac MRI scans and blood tests (troponin levels) to measure damage and swelling. The goal was to find links between the two methods…

This study looked at 70 adults having open heart surgery to compare two types of heart-lung machines: a newer, less invasive one versus the standard machine. The goal was to see which method better protects the body's tissues and the brain during surgery. Researchers measured oxy…

This study looked at whether living in a hot climate affects bleeding after heart surgery. Researchers compared 400 Egyptian patients from hot regions (Upper Egypt) and moderate regions (Lower Egypt). They measured bleeding in the first 24 hours after surgery and recorded deaths …

This study looked at 102 adults having planned heart surgery to see if drops in brain oxygen levels during the operation are linked to memory or thinking problems afterward. Researchers measured brain oxygen with a special monitor and tested thinking skills before and after surge…