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Heart surgery fluid trick may cut complications

NCT ID NCT07466082

First seen Mar 23, 2026 · Last updated Jun 22, 2026 · Updated 15 times

Summary

This study tested whether using a noninvasive monitor called Pleth Variability Index (PVI) to guide fluid replacement during heart surgery could improve outcomes. Eighty patients undergoing cardiac surgery received a technique called acute normovolemic hemodilution, where some blood is removed and replaced with fluids. The goal was to see if PVI guidance leads to more precise fluid management and fewer complications like kidney injury or the need for blood transfusions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Bursa City Hospital

    Bursa, Nilüfer, 16110, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acute normovolemic hemodilution (ANH) guided by Pleth Variability Index

What this could lead to

If successful, this approach could help surgeons manage fluids more precisely during heart surgery, potentially reducing complications and the need for blood transfusions.

What could go wrong

This is a small, completed study with 80 participants, so results may not apply to all patients. The technique is not a treatment for a disease but a method to improve surgical outcomes.

Conditions

The condition(s) this trial relates to.

Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.