Heart surgery fluid trick could cut transfusions and complications
NCT ID NCT07466082
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using a device called the Pleth Variability Index (PVI) to guide a blood-saving technique (acute normovolemic hemodilution) during heart surgery leads to better fluid balance and fewer complications. Eighty patients undergoing cardiac surgery were enrolled. The goal was to see if PVI guidance reduces the need for blood transfusions and lowers the risk of problems like kidney injury.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- acute normovolemic hemodilution (blood removal and fluid replacement)
- What this could lead to
- If successful, this approach could help heart surgery patients receive fewer blood transfusions and have fewer complications like kidney injury.
- What could go wrong
- This is a small, completed study with 80 participants, so results may not apply to all heart surgery patients. The technique also carries risks of hemodynamic instability if not managed carefully.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE NORMOVOLEMIC HEMODILUTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bursa City Hospital
Bursa, Nilüfer, 16110, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could continuing a common heart drug before surgery save lives?
- Could waking up in the operating room speed heart surgery recovery?
- Can a simple frailty check predict how well seniors recover from heart surgery?
- Could a simple scheduling change ease heart surgery nerves?
- Can a robotic suit restore walking after stroke or spinal injury?
- Calcium timing during bypass may cut need for heart drugs