CARDIAC SURGERY

This study tests whether giving a single dose of intravenous iron the day after heart surgery can reduce the chance of long-term anemia. About 180 adults with low iron or anemia before surgery will take part. Half will get the iron infusion, half a placebo, and researchers will c…

This study looks at two different IV fluids given during heart surgery to see which one is safer for the kidneys. About 1,292 adults having heart surgery will be randomly assigned to receive either hydroxyethyl starch or a balanced crystalloid fluid. The main goal is to see which…

This study tests a new method to treat atrial fibrillation (a common heart rhythm problem) during open-heart surgery. About 200 adults having heart surgery will receive a special procedure that isolates the pulmonary veins using a device called GeminiS. The goal is to see if this…

This study tests whether giving a short infusion of amino acids during heart surgery can help prevent acute kidney injury, a common complication. Researchers will enroll 130 adults having elective heart surgery with a bypass machine. Half will receive standard care, and the other…

This study looks at whether foot massage or kinesio taping can help people aged 65 and older recover movement and reduce fear of moving after heart surgery. Sixty participants will receive one of these simple, drug-free treatments for seven days after surgery. The goal is to see …

This study looks at whether adding breathing exercises and muscle relaxation to standard care can help people who have had heart surgery feel less short of breath, less anxious, and have fewer symptoms of delirium. About 116 adults will take part, with half doing the extra exerci…

This study compares two ultrasound-guided nerve blocks to manage pain after heart surgery. 80 adults having planned heart surgery will receive one of the two blocks alongside standard anesthesia. The goal is to see which block reduces the need for strong painkillers (opioids) and…

This study looks at whether listening to guided meditation audio can lower stress and anxiety in people having open-heart surgery. About 72 adults will either receive the meditation sessions or standard care. Researchers will measure stress hormones, blood sugar, and anxiety leve…

This study will test whether giving methadone based on a patient's genes can reduce opioid side effects like nausea, vomiting, and breathing problems while improving pain control. Researchers will enroll 400 adults over 60 having heart surgery. The goal is to find the safest, mos…

This study tests a new type of nerve block (SPSIPB) to see if it can reduce pain and the need for strong painkillers after heart surgery. About 120 adults having planned heart surgery through a chest incision will be randomly assigned to get either the nerve block or standard car…

This observational study looks at how the anesthetic remimazolam affects brain function in older adults after heart surgery. Researchers will track confusion and memory problems in 210 patients aged 60 and older. The goal is to see if this drug reduces the risk of postoperative d…

This study looks at whether a special breathing technique (lung volume optimization maneuver) can improve heart and lung function in 80 children having heart surgery. The approach involves adjusting ventilator settings to find the best lung volume. Researchers will measure blood …

This study will check how accurate the Dexcom G7 continuous glucose monitor is in 100 adults having heart surgery. Participants will wear the device during their operation so researchers can compare its readings to standard lab tests. The goal is simply to measure performance, no…

This study looks at whether a Belgian policy change that started covering the cost of a clotting drug called fibrinogen changed how much blood patients need during complex heart surgery. Researchers will compare about 450 adults who had surgery before and after the policy took ef…

This study will watch 100 heart surgery patients to learn why some develop serious gut issues. Researchers will track patients from hospital stay to discharge, looking for early warning signs and specific markers in the body. The goal is to better predict and diagnose these compl…

This study will compare two ultrasound-guided techniques (Direct vs. Seldinger) for inserting a small tube into the wrist artery of 242 adults undergoing heart surgery. The goal is to see which method succeeds on the first try more often in patients expected to have difficult acc…

This study looks at whether measuring antithrombin levels in the blood before heart surgery can predict if a patient will respond poorly to heparin, a blood thinner used during bypass. About 300 adults having planned heart surgery will give an extra blood sample, and researchers …

This study will observe 15,000 adults having heart surgery at hospitals worldwide. Researchers will track different anesthesia, heart-lung machine, and surgical methods to see which lead to better recovery and fewer complications. The goal is to gather real-world data to help cre…

This study will test if using a video laryngoscope (McGRATH) to insert a heart ultrasound probe causes less throat injury than the standard method (Macintosh laryngoscope). About 100 adults having elective heart surgery will take part. The main goal is to see which approach leads…