Meditation before heart surgery may lower stress hormones

NCT ID NCT07379944

Symptom relief Sponsor: University of Gaziantep Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether listening to guided meditation audio can reduce stress and anxiety in people having open-heart surgery. About 72 adults will either receive meditation sessions or standard care. Researchers will measure stress hormones, blood sugar, and anxiety levels before and after surgery to see if meditation helps.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Scheduled to undergo open-heart surgery * ASA physical status I-II * First-time cardiac surgery * On-pump, median sternotomy technique planned * Mild to moderate intraoperative hypothermia protocol * No diagnosed psychiatric disorder * Not using psychotropic medications * No endocrine disorders affecting cortisol (e.g., Addison's disease, Cushing's syndrome) * Not taking corticosteroid medications * Glasgow Coma Score = 15 postoperatively * No perioperative complications that may interfere with participation * Able and willing to provide informed consent Exclusion Criteria: * Prolonged or complicated surgery * Withdrawal of consent at any stage * Postoperative altered consciousness (GCS \< 15) * Perioperative administration of corticosteroids * Severe intraoperative complications * Surgery cancelled or rescheduled * Hearing impairment preventing participation in auditory intervention * Any condition clinically judged by the investigator to interfere with study participation

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder coronary artery disorder Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Cardiac surgery Coronary artery disease Postoperative stress Surgical stress response

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Meditation before heart surgery may lower stress hormones

What the study statuses mean