University Of Rochester

This completed study looked at how well licensed RSV vaccines (Pfizer's Abrysvo or GSK's Arexvy) trigger an immune response in adults over 60 living in long-term care facilities compared to those living independently in the community. Researchers measured antibody levels before a…

This study tests a short, three-session therapy program called ASSIP for adults who have attempted suicide within the past 60 days. The therapy helps participants understand the feelings and events leading up to their attempt and create a personalized safety plan. Researchers wan…

This study looked at whether denosumab, a drug usually used for bone health, could safely reduce the risk of smoldering multiple myeloma turning into active multiple myeloma. Twenty people with smoldering multiple myeloma took part. The goal was to see if the drug could lower the…

This study tested whether adding slow, paced breathing exercises to computer-based brain training could improve thinking skills and slow dementia in older adults with mild cognitive impairment. Over 8 weeks, 113 participants either did both breathing and brain training, brain tra…

This study tested a special team-based program called R-FACT for people with serious mental illness who are also involved with the criminal justice system. The program provides intensive, community-based support with close coordination between mental health and justice staff. Res…

This study tested whether a daily supplement called Avmacol Extra Strength, which contains sulforaphane from broccoli seeds, can slow kidney disease progression in people with stage 3 or 4 chronic kidney disease. The trial enrolled 96 adults and compared the supplement to a place…

This study tested a daily supplement of curcumin (from turmeric) and piperine (from black pepper) in 30 people with early-stage prostate cancer or pre-cancerous blood conditions (MGUS or low-risk smoldering multiple myeloma). The goal was to see if the supplement could lower canc…

This early study tested whether a dye called methylene blue, activated by a laser, can safely sterilize deep abscess cavities during standard drainage. Twenty-one adults with abscesses requiring drainage received the treatment. The main goal was to check for safety issues like ti…

This study tested a program called TEAM-UP that brings asthma specialist visits to children at school via telemedicine, combined with daily preventive medication given at school. 326 children aged 4-12 with moderate to severe asthma took part. The goal was to see if this approach…

This early-phase study tested whether repeated hyperbaric oxygen therapy is safe for multiple myeloma patients who are about to receive high-dose chemotherapy and a stem cell transplant. Twenty-nine participants were exposed to 100% oxygen at 2.5 times normal atmospheric pressure…

This study tested a telemedicine program to help children with asthma get better follow-up care after an emergency room visit. The program included a video visit at school within a week of discharge, plus two more check-ins. Researchers measured how many symptom-free days childre…

This study tested whether a special microscope (two photon microscopy) can detect leftover basal cell carcinoma during Mohs surgery as accurately as the usual lab method. 135 people having Mohs surgery for skin cancer took part. The goal was to see if the new imaging tool could g…

This study looked at whether adding Child-Parent Psychotherapy (CPP) to regular home visits by community health workers can improve parenting and prevent child maltreatment. It involved 222 low-income pregnant women at high risk. Researchers compared different start times (before…

This completed study tested whether a smartphone app called InBloom could help prevent postpartum depression in pregnant people at risk. 152 participants were randomly assigned to use the app or attend a weekly group program called ROSE. The study measured depression rates and se…

This study tested whether a home-based brain stimulation device (tDCS) could help prevent suicidal thoughts in adults recently discharged from the hospital for mood disorders. Thirty-three participants used the headset for 30 minutes a day over two weeks, supervised remotely. The…

This completed trial tested a program to increase COVID-19 vaccination among pregnant women. Over 6,900 participants were involved across OB/GYN practices. The program included training for healthcare providers, reminders, and feedback on vaccination rates. The goal was to see if…

This pilot study tested whether taking a green tea extract (EGCG) plus vitamin C daily for 12 weeks is safe and feasible for older cancer survivors who are frail or pre-frail. The study enrolled 24 people aged 65 and older who had completed cancer treatment. The main goal was to …

This study tested a program called Cuidando Juntos, designed to support Latino caregivers of people with dementia. The program includes eight modules on stress management, self-care, and handling difficult behaviors. Researchers wanted to see if the program was well received and …

This pilot study tested whether a mobile exercise app (GO-EXCAP) is feasible for older patients (60+) with myeloid neoplasms who are receiving chemotherapy. 25 participants used the app for 7 weeks. The goal was to see if patients would actually use the app and stick with the pro…

This study tested whether a pharmacist-led program could safely reduce the number of unnecessary medications taken by older adults (65+) with curable cancers starting chemotherapy. 51 patients participated, with oncologists randomly assigned to either a pharmacist review or a sim…

This study tested whether a personalized computer program (PEP) could improve attitudes toward technology and engagement with cognitive training in 49 older adults with mild cognitive impairment living in senior communities. Participants first used PEP or a control activity for 4…

This study tested whether a therapy called dialectical behavior therapy (DBT) is helpful and acceptable for teens aged 14–17 with fetal alcohol spectrum disorders (FASD). Nine teens and their caregivers took part in a program that included individual therapy, group skills trainin…

This study tested a program called Social Engage (S-ENGAGE) designed to help Spanish-speaking Latino adults who feel socially isolated and have suicidal thoughts. The program uses action planning to help participants set goals and take steps to increase their cultural-social acti…

This study tested a smartphone app called FMF Connect for parents and caregivers of children with fetal alcohol spectrum disorders (FASD). The app provides helpful information and peer support to manage children's behavior. 129 parents participated, and researchers measured chang…

This study tested whether a brain-training technique called neurofeedback could help children aged 6 to 12 who have experienced trauma. Forty children already receiving therapy also did neurofeedback sessions. Researchers measured changes in trauma, depression, and anxiety sympto…

This study looked at whether exercise or nutrition education can reduce nerve pain caused by chemotherapy in women with breast cancer. 80 women took part in a phase 2 trial comparing the two approaches. The goal was to see if these lifestyle changes could help manage symptoms and…

This study tested a coaching program called Social Engage Coaching for adults aged 60 and older who feel lonely and have had thoughts of suicide. The program involves up to 10 one-on-one sessions with a trained coach to help build social connections. Researchers measured loneline…

This study tested a telehealth program called Dyadic Life Review (DLR) for older adults (65+) with advanced cancer and mild cognitive impairment, along with their caregivers. The program involved 8 weekly video sessions where patients and caregivers shared memories from different…

This study tested a brief psychotherapy called Social Engage for Hispanic/Latino caregivers aged 40 and older who care for a family member with dementia and feel lonely or stressed. Ten participants received up to 8 weekly sessions by phone or video over 3 months. The goal was to…

This study tested whether computer-based visual exercises can help people with schizophrenia who have trouble with contrast sensitivity and organizing visual information. Researchers compared several training programs, including one called UltimEyes, in 79 participants. The goal …

This study used body-worn sensors to track movement in 132 people with early, untreated Parkinson's disease over 12 months. The goal was to see if digital measurements could accurately measure disease progression and match standard clinical assessments. The findings may help deve…

This study tested a tool called UR-GOAL to help older patients with acute myeloid leukemia (AML), their caregivers, and their doctors communicate better and make decisions together. It involved 161 participants aged 60 and older. The goal was to see if the tool improved shared de…

This study looked at whether a software program called Carevive could help patients with advanced kidney cancer track side effects from their oral targeted therapy or immunotherapy. 21 patients used the software to report symptoms and received self-care tips. The goal was to see …

This pilot study tested a communication tool called UR-GOAL in 15 older adults (age 60+) with newly diagnosed acute myeloid leukemia (AML), along with their caregivers and doctors. The tool helps patients share their preferences and goals, so treatment decisions better match what…

This pilot study looked at whether older adults with mild cognitive impairment (MCI) find music training programs acceptable and enjoyable. Nineteen participants took part in 12 weeks of piano or music lessons, with home practice and mood tracking. The goal was to see if people w…

This study tested a program to help older patients (age 60+) with blood cancers plan their future medical care while in the hospital. The program focused on completing advance directives and healthcare proxy forms. Out of 41 participants, the study found that the program was feas…

This study tested whether a telehealth program could help older patients (60+) with acute myeloid leukemia or myelodysplastic syndrome discuss and document their future medical wishes. Researchers enrolled 36 patients, caregivers, and clinicians to see if the program was easy to …

This study tested a program called DIAL-SDM that trains kidney doctors and coaches older patients (65+) with advanced kidney disease to have better conversations about dialysis. The goal was to see if the program was practical and acceptable. 102 patients, their caregivers, and 2…

This study looked at vitamin B6 levels in 288 people with Parkinson's disease. Researchers wanted to find out how common abnormal B6 levels are and whether they relate to age, sex, race, or other factors. The study did not test any treatment—it only measured and compared B6 level…

This study tested an online program called SOPHIE that uses virtual patient scenarios to help clinicians improve their communication skills. 51 clinicians and trainees were randomly assigned to either the simulation training or standard educational materials. Their communication …

This study looked at whether silent myocardial ischemia (reduced blood flow to the heart without chest pain) increases the risk of heart problems or death in people with coronary heart disease. Researchers followed participants for one to three years. The goal was to better under…

This study looked at whether community organizations can successfully run a healthy lifestyle program called Deaf Weight Wise (DWW) for Deaf adults who use American Sign Language. The program involved 16 weekly group sessions led by a trained Deaf counselor via Zoom. Researchers …

This study tested whether a home rehabilitation program, with daily activity tasks and heart rate monitoring sent by text or email, helps people recover better after a serious blood clot in the lung (pulmonary embolism). 32 adults who had been hospitalized for this condition took…