Could a blue dye and laser zap abscess bacteria?

NCT ID NCT02240498

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tested whether a dye called methylene blue, activated by a laser, can safely sterilize deep abscess cavities during standard drainage. Twenty-one adults with abscesses requiring drainage received the treatment. The main goal was to check for safety issues like tissue damage or dye leakage, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methylene blue

What this could lead to

If it works, this could provide a new way to kill bacteria in deep abscesses during drainage, potentially reducing the need for repeated procedures or stronger antibiotics.

What could go wrong

This is a very early phase 1 safety study with only 21 participants. It is not designed to prove effectiveness, and there are risks like damage to surrounding tissue or adverse reactions to methylene blue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

abscess

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States