University Of Rochester

This study is testing whether a few doses of ketamine, given alongside guided therapy sessions, can help people with treatment-resistant depression. Researchers want to see if this combination changes brain activity in ways that reduce depression symptoms and improve emotional fl…

This study aims to find the best caffeine dose to help extremely premature babies breathe better and avoid serious complications. Researchers will compare a higher dose to the standard dose in 40 infants born before 28 weeks. The goal is to see if the higher dose improves oxygen …

This early-stage study is testing whether amlodipine, a medication typically used for high blood pressure, is safe and might help people with myotonic dystrophy type 1. Researchers want to see if the drug can improve muscle strength, reduce stiffness, and help with daily activiti…

This study is testing if adding a special light-activated treatment to the standard drainage procedure helps breast abscesses heal faster. Fifty adults with a breast abscess will be randomly assigned to receive either the standard drainage alone or the standard drainage plus the …

This study aims to find out which of two different breast pumping schedules works better to help increase milk production for parents struggling with low supply. Researchers will enroll about 225 breastfeeding parents of babies under 3 months old. They will also study the body's …

This study is testing a new school-based program to help children with asthma. It provides a single, easy-to-use inhaler at school for both daily prevention and quick relief of symptoms. Researchers will compare this program to usual care to see if it reduces emergency room visit…

This study is testing whether a combination of three drugs—cladribine, low-dose cytarabine, and venetoclax—can help control acute myeloid leukemia (AML) in adults whose cancer has returned or didn't respond to previous treatment containing venetoclax. The goal is to see if this r…

This study is for people whose first atrial fibrillation (AFib) ablation procedure didn't work. It compares two approaches for the second attempt: the standard repeat procedure versus adding treatment to an extra area of the heart. The goal is to see which method better reduces s…

This study is testing whether adding a special light treatment to the standard procedure for draining deep abscesses helps patients heal faster. The treatment involves applying a blue dye to the infection and then shining a red light on it to kill bacteria. Researchers will compa…

This study compares two ways to treat anemia before heart surgery: taking oral iron capsules at home versus receiving standard intravenous iron injections at the hospital. Researchers want to see if the oral treatment works as well as the IV treatment at increasing red blood cell…

This study is testing whether a special green dye can safely and effectively help surgeons see the first lymph nodes that cancer might spread to in children with solid tumors. During surgery, the dye is injected near the tumor and glows under a special camera, highlighting these …

This study is testing if offering a simple, at-home style HPV test during an emergency room visit can help more people get screened for cervical cancer. It will enroll about 200 women and transgender/non-binary individuals with a cervix, aged 30-65, who are overdue for screening.…

This study is testing if performing a preventive heart procedure (called VT ablation) soon after implanting a defibrillator can reduce dangerous, fast heartbeats in high-risk patients with heart failure. About 62 participants will be randomly assigned to either get the preventive…

This study is testing whether an enhanced training program for National Guard leaders can help prevent suicide and crises among soldiers. The program teaches leaders how to have better conversations with their soldiers, spot signs of distress, and provide support. Researchers wil…

This study aims to see if a simple program can get more people screened for lung cancer. It will work with 300 eligible patients in an emergency department who are current or former heavy smokers. Researchers will test if providing a direct referral to a screening program plus se…

This study aims to see how a non-invasive brain stimulation treatment called rTMS affects brain activity and symptoms in people with fibromyalgia. Researchers will use MRI scans to measure changes in the brain's motor areas after stimulation on either the left or right side. They…

This study is testing whether medical cannabis can help reduce nausea in adults receiving chemotherapy that commonly causes severe sickness. About 50 participants will be randomly assigned to start using medical cannabis vapor either immediately or after one chemotherapy cycle, w…

This study is testing a program called SONATA that involves a patient's friends and family to provide better support. It aims to see if this social network approach helps older adults with advanced cancer feel more confident managing their care and improves their emotional well-b…

This study is testing a brief, two-session online therapy program designed specifically for Deaf adults. The goal is to see if this therapy can help change negative beliefs about mental health treatment and encourage more people to seek professional help. Researchers will also ch…

This study is testing a new program called Thrive, designed to help young adults with fetal alcohol spectrum disorders (FASD). The program uses a person-centered planning approach, where participants invite their support network to help them make plans to meet personal goals. Res…

This study is testing a culturally adapted online program called Tele-Savvy for Latino caregivers of people with Alzheimer's or dementia. The program aims to help caregivers build skills and confidence through weekly group video sessions and instructional videos. Researchers want…

This study is testing whether a personal coaching program helps adults aged 60 and older feel more socially connected and less lonely. Participants will be randomly assigned to receive 10 coaching sessions or be placed on a waitlist. The main goal is to see if coaching improves f…

This study is testing three different programs to help older cancer survivors who have memory and thinking problems after treatment. Researchers will compare exercise training, brain training, and a combined program against usual care to see which works best. The goal is to find …

This study is testing a new disposable eye cover, called the BriTer Eyez Moisture Vue, to see if it helps people with mild to moderate dry eye. Researchers will have 35 participants wear the device for two hours to check if it improves tear quality and reduces dry eye symptoms. T…

This study is testing whether following a strict whole food, plant-based diet for 26 weeks can improve quality of life and general health in women with metastatic breast or endometrial cancer. Sixty participants will be randomly assigned to either follow the special diet with coa…

This study aims to find out if a simple bedside test that measures pain sensitivity can help predict which of two common pain medications will work better for an individual. Researchers will test 190 adults with long-term nerve pain in their feet from conditions like diabetes or …

This study aims to understand how Duchenne muscular dystrophy (DMD) affects babies and toddlers in their first three years of life. Researchers will follow 105 boys with DMD, tracking their motor skills, language development, and when they start treatments. The goal is to gather …

This study aims to understand if a person's body composition (like weight and fat distribution) is linked to how their airways react during a specific breathing test. Researchers will measure airway function in 100 people who are already scheduled for a standard methacholine chal…