University Of Rochester

This study tests whether a whole food, plant-based diet can improve quality of life and dietary habits in 60 women with metastatic breast or stage IV endometrial cancer. Participants will receive nutrition education and food delivery, and researchers will track diet adherence and…

This study tests giving asthma medicine to children at school to improve their health and reduce disparities. About 300 children aged 4-12 with asthma will take part in Rochester City School District. The goal is to see if this approach helps control asthma better and is cost-eff…

This study tests whether adding a special light treatment (methylene blue photodynamic therapy) to standard drainage can help breast abscesses heal faster. About 50 adults with breast abscesses will be split into two groups: one gets standard care alone, the other gets standard c…

This study tests whether adding a special light-activated blue dye treatment to the usual drainage procedure can help clear deep abscesses faster. About 120 adults with abscesses needing drainage will be split into three groups: one gets the standard drainage alone, another gets …

This study tests a combination of three drugs (cladribine, low-dose cytarabine, and venetoclax) in 24 adults with acute myeloid leukemia (AML) that has come back or not responded to prior treatment, especially after a venetoclax-based regimen. The goal is to see if this combo can…

This study looks at whether giving a higher dose of caffeine to extremely premature babies (born before 28 weeks) can improve their breathing and lower the risk of serious problems like lung disease or brain injury. About 40 infants will be randomly assigned to receive either the…

This study tests whether an oral iron supplement (sucrosomial iron) works as well as intravenous (IV) iron to boost red blood cell counts in 75 anemic patients scheduled for heart surgery. Participants will be randomly assigned to receive either the oral pill or the standard IV t…

This study tests if ketamine, given alongside psychotherapy, can help people with depression that hasn't improved with other treatments. About 25 adults will receive 1-2 doses of ketamine and 3-4 therapy sessions. Researchers will use brain scans and surveys to see if the treatme…

This study looks at whether a simple home exercise program can improve daily function in people with pulmonary hypertension caused by interstitial lung disease. About 30 adults will follow a 16-week exercise plan from home. Researchers will measure how efficiently the heart works…

This study tests a disposable moisture chamber worn over glasses for 2 hours in 35 adults with mild to moderate dry eye disease. Researchers will measure tear film stability, tear volume, and symptom scores before and after wear to see if the device provides short-term relief.

This early-stage trial tests whether amlodipine, a blood pressure medication, can safely improve muscle strength and reduce stiffness in 20 adults with Myotonic Dystrophy Type 1. Participants take the drug for 10 weeks, with doses adjusted partway through. The main goal is to che…

This study tests whether adding the allergy drug diphenhydramine (Benadryl) to standard sedation medicine can reduce pain during a first-trimester abortion procedure. About 98 adults having an abortion at 13 weeks or earlier will receive either diphenhydramine or a placebo alongs…

This study tests a two-session, Zoom-based therapy designed for Deaf adults who use American Sign Language. The goal is to change negative beliefs about mental health treatment and encourage people to seek help. Researchers hope this will reduce suicide risk and improve symptoms …

This study will test two different breast pumping routines in 225 parents who have low milk supply. Researchers want to see which routine works better and also study the hormones and cells that control milk production. The goal is to find better ways to help parents make enough m…