Personalizing leukemia care for seniors: a fitness-based treatment strategy put to the test

NCT ID NCT07735208

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether using a comprehensive geriatric assessment to guide treatment selection can reduce side effects and improve outcomes in adults aged 60 and older with newly diagnosed acute myeloid leukemia. Participants are classified as fit, vulnerable, or frail, and receive predefined treatment regimens based on their assessment. The study compares this approach to standard oncologist-directed care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
geriatric assessment-guided treatment regimens
What this could lead to
If successful, this approach could help doctors choose safer, more effective treatments for older AML patients based on their overall health, not just age.
What could go wrong
This is a mid-stage trial with 120 participants, so results may not apply to all older adults. The benefit of GA-guided treatment over standard care is not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • University of Rochester Medicine

    Rochester, New York, 14642, United States

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