University Of Rochester

This study is testing a modified, potentially less harsh chemotherapy combination for patients aged 75 and older with an aggressive type of blood cancer called DLBCL. The goal is to see if adding a targeted drug (polatuzumab vedotin) to a reduced-dose standard regimen is effectiv…

This study is testing a new visual training program designed to help people who lost part of their vision after a stroke. Researchers will first try the training with people who have normal vision, then with stroke survivors, to see if it can improve visual abilities. The goal is…

This study aimed to see if using a shorter, gentler course of chemotherapy before surgery could effectively treat early-stage HER2-positive breast cancer. The plan was to give patients four cycles of chemo and targeted drugs before surgery, then adjust the follow-up treatment bas…

This study aimed to test a precise, high-dose radiation treatment for prostate cancer that returns only in the prostate after initial radiation therapy. It planned to treat only the visible tumor spots, not the whole prostate, to see if this controlled the cancer and was safe. Th…

This study is testing whether training 'peer coaches' can help patients with limited health literacy have better conversations with their doctors about reducing their risk of heart disease. The study involves 60 patients at a single clinic who are at risk for heart problems. Half…

This study is testing whether adding a specific chemotherapy regimen (mFOLFOX6) before the usual treatment can help stop esophageal cancer from spreading to other parts of the body. It involves 40 adults with locally advanced but potentially removable esophageal cancer. The goal …

This study is testing if using a small, implanted heart monitor helps doctors better manage irregular heartbeats (atrial fibrillation or AFib) after a common procedure called catheter ablation. The monitor sends data to doctors, allowing for quicker treatment adjustments. The goa…

This study aims to understand how repeated, non-concussive head impacts in sports affect brain function and to test ways to protect it. It will enroll 350 college athletes from contact sports like football and soccer, along with some non-contact athletes for comparison. Researche…

This study aims to find the best ways for doctor's offices to use team-based home blood pressure monitoring. It involves 5,760 patients with high blood pressure who will regularly send their home readings to their care team. Researchers will test different support strategies to s…

This study is testing whether a small, implanted heart monitor can find hidden, irregular heartbeats (atrial fibrillation) in people with heart failure. Finding these rhythm problems early could allow doctors to start treatments like blood thinners to prevent strokes and hospital…

This study is testing whether a training program called Wingman-Connect can help prevent suicide attempts among new Air Force members. The program aims to strengthen social bonds and healthy coping skills. Researchers will track suicide attempt rates at 8 Air Force bases as the p…

This study is testing a group training program called Wingman-Connect, designed to prevent suicide among U.S. Air Force personnel. Nearly 3,000 Airmen in technical training classes will be randomly assigned to receive either this program or a standard training course and will be …

This study is testing if offering a simple, at-home HPV test kit to women visiting the emergency room can help more people get screened for cervical cancer. Researchers are focusing on women aged 25-65 who may not get regular check-ups. The goal is to see if this convenient optio…

This study tests whether training school staff to communicate about vaccines and providing promotional materials increases flu vaccination rates among students. It involves 6,000 students across multiple schools, with some schools receiving the training and materials while others…

This study is testing whether a combined mobile exercise and memory training program is practical and helpful for older cancer survivors who have completed treatment. It aims to see if this approach can improve thinking and memory problems that sometimes occur after cancer therap…

This study is testing a workplace health program designed to improve the overall well-being of sign language interpreters. It enrolled 133 certified interpreters to see if a specialized program works better than general health information. The goal is to find effective ways to su…

This study is testing whether online training for community neurologists and telemedicine support services can improve quality of life for people with Parkinson's disease, Lewy Body Dementia, and related conditions, and reduce the burden on their caregivers. It involves over 600 …

This study aims to find out if placing a small tube (drain) during a common neck surgery for children leads to better recovery. Kids having surgery to remove a congenital neck cyst will be randomly assigned to have the surgery with or without a drain. Doctors will then track thei…

This study aims to understand how vision changes in the year after a stroke damages the part of the brain that processes sight. Researchers will track 60 people who have had a stroke affecting their vision, measuring changes in their eyes, brain, and visual abilities over time. T…

This study aims to understand how the brain processes what we see by observing the link between eye movements and attention. Researchers will track the eye movements of 20 healthy adults while they perform simple visual tasks on a computer screen. The goal is basic research to le…