New hope for seniors with aggressive blood cancer: targeted combo shows promise

NCT ID NCT04594798

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding a targeted drug called polatuzumab vedotin to a standard chemotherapy regimen (R-miniCHP) can help people aged 75 and older with a type of lymphoma called DLBCL. The goal is to see if the combination improves how long patients live without their cancer getting worse. The study enrolled 39 participants and is currently active but no longer recruiting.

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Conditions

The condition(s) this trial relates to.

B-cell neoplasm diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement Richter transformation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Rochester

    Rochester, New York, 14642, United States