Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could your own blood cure dry eye? plasma drops put to the test

NCT ID NCT05121493

Symptom relief Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether eye drops made from a patient's own platelet-rich plasma can improve dry eye symptoms. Participants with dry eye syndrome will receive either platelet-rich plasma drops or plasma drops without platelets. The trial measures changes in vision, tear film quality, and eye surface temperature to see if the drops help.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
platelet-rich plasma tear drops and platelet-poor plasma tear drops
What this could lead to
If effective, these drops could offer a new treatment option for people with dry eye syndrome.
What could go wrong
This is a small, early-stage study, so results may not apply to everyone. The drops are made from the patient's own blood, which limits availability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects must be diagnosed with clinically significant dry eye. * Subjects have no active ocular disease or allergic conjunctivitis. * Subjects must not be using any topical ocular medications within two weeks prior to enrollment. * Subjects must be willing and able to follow instructions. * Subjects must have voluntarily agreed to participate in the study by signing the statement of informed consent. * Subjects must meet plasma donor criteria as established by University of Rochester Transfusion Medicine \& Blood Bank. Exclusion Criteria: * Is pregnant at the time of enrolment in the study determined by urine pregnancy test. * Is currently on a course of antibiotics * Is considered by the Investigator to not be a suitable candidate for participation and are not at risk for glaucoma. * Is considered by the University of Rochester Transfusion Medicine \& Blood Bank not a suitable candidate for blood donation.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dry eye syndromes are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

dry eye syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry eye syndromes

Contacts and locations

Locations

  • Flaum Eye Institute at the University of Rochester

    Rochester, New York, 14642, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.