University Of Illinois At Chicago

This 12-month trial compares two weight-loss strategies in adults with obesity: eating only between 12 pm and 8 pm each day (an 8-hour time-restricted eating window) versus reducing daily calories by 25%. A control group follows no specific diet. The study measures changes in bod…

This study investigates whether following the DASH diet—a heart-healthy eating plan—can improve quality of life for adults whose asthma is not well controlled by medication. Participants are randomly assigned to either a DASH-focused behavioral coaching program or standard asthma…

This trial tests a smartphone app called Tappt that uses smart tags to help people with hepatitis C stick to their daily oral medication. Participants scan tags each time they take a dose, and the app tracks adherence. The study compares their results to historical data from simi…

This study looked at whether a progressive resistance training program could help older adults with sarcopenia (age-related muscle loss) control their high blood pressure. 77 sedentary adults aged 60 and older participated. The goal was to see if building muscle strength could be…

This study looked at whether giving underserved patients with type 2 diabetes a continuous glucose monitor (CGM) plus monthly telehealth visits with a pharmacist helps them manage their blood sugar better. 46 adults with uncontrolled diabetes took part. Researchers compared those…

This early-phase study tested a combination of two drugs, venetoclax and omacetaxine, in 6 adults with acute myeloid leukemia (AML) whose cancer had stopped responding to venetoclax-based treatments. The main goal was to find the safest dose of omacetaxine when given with venetoc…

This study compared time-restricted eating (eating only during a 6-8 hour window each day) to daily calorie restriction for weight loss and blood sugar control in 32 adults with type 1 diabetes and obesity. Participants followed their assigned diet while continuing insulin and gl…

This study looked at whether smokers who want to cut down can switch to a special research e-cigarette and smoke fewer regular cigarettes. Over 12 weeks, researchers tracked how many cigarettes people smoked and if any quit completely. The goal was to see if e-cigarettes are a he…

This study tested a mobile phone app called 'My Personal Health Guide' that uses a friendly, talking avatar to help African American men who have sex with men (ages 18-34) stick to their HIV medication and stay in care. The app provides private, easy-to-understand information and…

This study looked at whether high-intensity breathing exercises (inspiratory muscle training) can improve blood vessel function and artery stiffness in people with heart disease before they start cardiac rehab. Eleven adults who had heart surgery or related conditions took part. …

This study tested whether eating only during an 8-hour window each day (time-restricted eating) helps young adult survivors of childhood cancer manage their weight. Thirteen survivors participated to see if this approach is safe, doable, and acceptable. The goal is to reduce obes…

This study tested whether alternate day fasting (eating only 600 calories on fast days) combined with regular aerobic exercise can reduce liver fat in people with non-alcoholic fatty liver disease (NAFLD). Eighty obese adults aged 18–65 with NAFLD participated. The goal was to se…

This study compares group antenatal care to standard individual care for pregnant women in Malawi. In group care, women of similar pregnancy stage meet together for a two-hour visit that includes self-checks, a brief private consultation, and interactive health education. The goa…

This study looked at whether a Mediterranean diet, weight loss, or both could lower colorectal cancer risk in 180 obese African Americans aged 45-75. Participants followed one of four plans for six months, and researchers measured changes in bile acids, gut bacteria, and cell act…

This study tested whether taking a daily supplement of lactoferrin (a protein found in milk) can help prevent iron deficiency anemia in pregnant women with obesity. 23 women at risk for anemia took part from mid-pregnancy through labor. The main goal was to see if the approach wa…

This study looked at whether the Big Brothers Big Sisters community mentoring program can prevent crime and delinquency in youth ages 10 to 16. Over 1,300 young people were randomly assigned to either get a mentor or not, and researchers tracked arrests, delinquency, and substanc…

This trial tests a computer-based tool called PAINRelieveIt for adults with sickle cell disease, a condition that causes intense pain episodes. The tool has three parts: one helps patients report their pain, another educates them about pain management, and a third helps doctors c…

This study looks at whether following a Mediterranean diet can help reduce chronic pain in people with sickle cell disease. About 30 adults with sickle cell disease who have pain most days will try the diet and report their pain levels. Researchers will also check changes in gut …

This study tested a 4-month remote exercise program designed for African-Americans with multiple sclerosis living in rural areas. 121 participants were randomly assigned to either the exercise program or a stretching control group. The goal was to see if the program could improve…

This study tested a 6-week program called BUILT for families with children aged 6 to 12 who have ADHD. The program teaches healthy habits around sleep, nutrition, and exercise to help improve focus and behavior. Researchers measured changes in physical activity, sleep, diet, and …

This study looked at whether high-intensity walking exercise can help reduce fatigue and improve walking in people with multiple sclerosis (MS). Twelve adults with MS who had walking problems and significant fatigue took part. Researchers measured changes in fatigue, walking spee…

This study looked at whether giving head and neck cancer patients a special nutritional supplement (Nestle IMPACT AR) before and after major surgery could lower the chance of wound problems like infections or poor healing. Only 4 people took part, and researchers tracked complica…

This study tested whether guided relaxation and acupuncture can reduce chronic pain and opioid use in adults with sickle cell disease. About 360 participants across three health centers were randomly assigned to one of these therapies or usual care. The goal was to see if these m…

This study tested a 6-week program called Heart Up! that uses text messages and social support to help adults with heart disease become more physically active and feel less hopeless. About 224 patients who had a heart attack or related procedure took part. The program aimed to im…

This early-stage study tested the safety of eye drops made from stem cell secretions in 9 adults with chronic corneal surface disease that did not improve with standard treatments. The drops were given in increasing doses to find the safest amount. Researchers checked for side ef…

This study tested whether an AI voice coach called Lumen can help adults with mild-to-moderate depression or anxiety. 200 participants were randomly assigned to receive problem-solving training from Lumen, a human coach, or a waitlist. The goal was to see if the AI coach could im…

This study tested a mobile app called WeCanManage designed to help cancer survivors with disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma used the app and reported on how helpful and easy i…

This study tested whether a 6-week digital sleep extension program could help young urban adults (ages 18-30) with mood symptoms like anxiety and depression get better sleep and feel better. Participants received weekly phone coaching and educational materials, and their sleep wa…

This study tested a computer program called PAINRelieveIt to help hospice patients with cancer pain. 262 patient-caregiver pairs used the touchscreen software to report pain and track medications. The goal was to see if it improved pain control, medication adherence, and satisfac…

This pilot study tested whether a mindfulness program could help reduce colorectal cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods and have had a colon polyp. Twenty-four women participated to see if the program was feasible and acceptab…

This study tests whether a high-protein breakfast and morning exercise, alone or together, improve children's focus and behavior in the classroom. About 40 children aged 6-11 will be split into four groups: both breakfast and exercise, breakfast only, exercise only, or neither. R…

This study is creating a digital program to help East Asian immigrants with cancer build resilience and start conversations about advance care planning with their families. Researchers will interview religious leaders and test the tool with 84 patients to see if it is easy to use…

This study follows people with Sturge-Weber syndrome, a rare condition that can cause seizures, strokes, and brain damage. Researchers collect medical records, brain scans, and blood samples over time to spot patterns linked to worsening symptoms. The goal is to find biological m…

This study looked at whether brain activity patterns can predict how well people with major depression or social anxiety respond to cognitive behavioral therapy (CBT). Over 200 participants were randomly assigned to 12 weeks of CBT or supportive therapy. Researchers measured brai…

This study looked at whether a training program on cultural humility and social justice for volunteer mentors can improve their relationships with youth of color. Over 800 mentors, youth, and parents participated. The program included online courses, live training, and extra supp…

This study tested a technique called ischemic conditioning, where a cuff around the thigh briefly restricts blood flow, to see if it can improve brain activity and leg function in people who had a stroke. Twenty participants with a stroke at least six months prior completed two s…

This study tested whether a smartphone app that tracks how you type (speed, backspace use, autocorrect) can help monitor mood and thinking problems in people with mood disorders like depression or bipolar disorder. 132 adults aged 25-50 took part. The goal was to see if this simp…

This study followed 82 people with blocked arteries supplying the back of the brain to see if low blood flow raises the risk of stroke or mini-stroke. Participants had already experienced a stroke or transient ischemic attack (TIA) and had at least 50% blockage in those arteries.…

This study looked at how two different diets affect gut bacteria and markers linked to colon cancer risk in 15 African American adults at higher risk. Participants ate a high-fat, animal-based diet and a low-fat, plant-based diet for three weeks each. Researchers measured changes…

This study tested a simple parenting program called 'Sit Down and Play' in a primary care clinic for low-income families. Over 12 months, 60 parents with young children were randomly assigned to receive the program or a safety handout. Researchers measured changes in parent-child…

This study tested a website designed to help people with advanced cancer and their family caregivers talk about advance care planning. Researchers worked with 36 patient-caregiver pairs to see if the website was easy to use and helpful. The main goal was to gather feedback to imp…

This study looked at how Chinese Americans talk about advance care planning—decisions about end-of-life care—with their families. Researchers interviewed religious leaders, patients with chronic diseases, and family caregivers in Chicago to understand their needs and readiness. T…

This study tested new guidelines for PSA screening to help doctors decide when to start and stop screening, how often to repeat it, and when to refer for biopsy. Researchers also provided patient navigation for men with elevated PSA levels. The goal was to see if these steps coul…

This study tested whether stabilizing hormones with estrogen patches and progesterone pills could reduce suicidal thoughts in women with recent suicidal ideation. 124 women participated, tracking their daily mood and suicide risk over a month. The goal was to understand how natur…

This study tested whether teens on probation would use a meditation app called Bodhi AIM for one month. Researchers wanted to see if it was possible to collect data remotely on cannabis use, sexual health, and mental health. The study involved 107 teens aged 13-18 in Cook County,…