University Of Illinois At Chicago

This study looked at whether alternating between fasting days and eating days, combined with exercise, could help people with non-alcoholic fatty liver disease (NAFLD) and obesity. Researchers measured changes in liver fat, weight, and blood markers in 80 participants. The goal w…

This small study tested whether 4 weeks of high-intensity breathing exercises (inspiratory muscle training) could improve blood vessel health in 11 adults with heart disease, such as those who had bypass surgery. Participants either did the real breathing workout or a sham versio…

This study tested a mobile phone app called 'My Personal Health Guide' that uses a friendly talking avatar to help African American men who have sex with men (ages 18-34) stick to their HIV medication and keep up with doctor visits. The app provides private, easy-to-understand su…

This early-phase study tested a combination of two drugs (venetoclax and omacetaxine) in 6 adults with acute myeloid leukemia (AML) whose cancer had stopped responding to standard treatments. The main goal was to find a safe dose of omacetaxine when given with venetoclax. Researc…

This study looked at whether giving head and neck cancer patients a special nutritional drink (Nestle Impact AR) before and after major surgery could lower the chance of wound complications like infections or fluid buildup. Only 4 people took part, and the goal was to see if the …

This study tested a program that gave people with uncontrolled type 2 diabetes a continuous glucose monitor and monthly video visits with a pharmacist. The goal was to see if this approach could help lower blood sugar levels in patients who have limited access to healthcare. 46 a…

This study tested a simple diet called time-restricted eating (TRE), where people eat only during a 6-8 hour window each day, against the standard daily calorie restriction diet. The goal was to see if TRE helps adults with type 1 diabetes and obesity lose weight and improve bloo…

This study looked at whether smokers who want to cut back can switch to a standardized research e-cigarette (SREC) and reduce their use of regular cigarettes over 12 weeks. 63 daily smokers aged 21+ who smoked at least 3 cigarettes a day for a year participated. Researchers track…

This study looked at whether eating only during an 8-hour window each day (time-restricted eating) helps young adult survivors of childhood cancer manage their weight. Some participants also took a fiber supplement. The goal was to see if this approach is safe, doable, and helpfu…

This study looked at whether the Big Brothers Big Sisters community-based mentoring program can help prevent crime and juvenile delinquency in youth ages 10 to 16. Over 1,300 participants were randomly assigned to either receive mentoring or not, and researchers tracked arrests, …

This study tested whether taking a daily supplement of lactoferrin, a protein found in cow's milk, could help prevent iron deficiency anemia in pregnant women with obesity. 23 women at risk for anemia took part. The main goal was to see if the approach was practical and acceptabl…

This study tested a mobile app called WeCanManage designed to help cancer survivors who have disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma used the app and reported on their symptoms and…

This study tested a computer program called PAINRelieveIt to help control cancer pain in hospice patients. It included 262 cancer patients and their caregivers. The program aimed to improve how well patients followed their pain medication plans and reduce pain intensity. Results …

This study tested a voice-enabled AI coach called Lumen that teaches problem-solving skills to adults with mild-to-moderate depression or anxiety. 200 participants were randomly assigned to receive coaching from Lumen, a human coach, or a waitlist. The goal was to see if the AI c…

This early-stage study tested the safety of eye drops made from stem cell secretions (secretome) in 9 adults with chronic corneal damage and reduced eye sensation. The goal was to find the highest safe dose and see if it helps heal the cornea's surface. Participants received incr…

This study tested whether guided relaxation or acupuncture can help reduce chronic pain and opioid use in people with sickle cell disease. About 379 adults with sickle cell disease and chronic pain took part across three hospitals. Participants were randomly assigned to receive g…

This study tested a 4-month exercise program done at home for Hispanic/Latino adults with multiple sclerosis (MS). The goal was to see if it could improve physical function, reduce fatigue, and boost quality of life. Thirty-three participants worked with coaches via video calls. …

This study tested a 6-week program called Heart Up! that uses text messages and support from nurses and loved ones to help adults with heart disease become more physically active and feel less hopeless. About 224 patients took part. The goal was to see if extra social support cou…

This study looked at whether high-intensity walking exercise can reduce fatigue and improve walking in people with multiple sclerosis (MS). Twelve adults with MS who had walking difficulties and significant fatigue took part. The goal was to see if this type of exercise could hel…

This study tested whether a 6-week digital sleep coaching program could help young adults (ages 18-30) who live in noisy, bright neighborhoods sleep longer and feel less anxious or depressed. Nineteen participants wore Fitbits and used a home sleep monitor while receiving weekly …

This study looked at how different diets affect gut bacteria and markers of colon cancer risk in 15 African American adults at higher risk for the disease. Participants ate both an animal-based diet high in fat and a plant-based diet low in fat to see changes in bacteria and bile…

This study tested a technique called ischemic conditioning, which uses a blood pressure cuff to briefly restrict blood flow to the leg, to see if it could improve brain activity and movement in people who had a stroke. Twenty participants with stroke completed two sessions, one w…

This study looked at people with narrowed or blocked arteries in the back of the brain, which can cause strokes or mini-strokes. Researchers used MRI scans to measure blood flow and see if those with low flow had a higher chance of another stroke. The goal was to better understan…

This study looked at how Chinese American patients with cancer or heart disease and their families discuss advance care planning. Researchers interviewed religious leaders and surveyed community members in Chicago to understand what support people need. The goal is to create a cu…

This study tested a program for parents of young children from low-income families. The program was delivered during regular doctor visits and aimed to help parents talk, read, and play more with their kids. Researchers wanted to see if the program was easy to use and if it impro…

This study tested new guidelines for PSA screening in 49 men aged 40-75 with elevated PSA levels. The goal was to improve how doctors decide when to start and stop screening, how often to repeat it, and when to refer for biopsy. Researchers compared PSA test rates, biopsy complic…

This study looked at 124 women with recent suicidal thoughts to understand how natural hormone changes during the menstrual cycle might increase suicide risk. Participants received a two-week hormone-stabilizing treatment to see if it reduced suicidal thinking around their period…

This study tested whether teens on probation would use a meditation app for one month and whether researchers could collect data remotely. 107 youth aged 13-18 participated. The goal was to see if this approach is feasible, not to measure health outcomes.

This study tested a website designed to help people with advanced cancer and their family caregivers have conversations about future medical care. Researchers worked with 36 participants to see if the tool was easy to use and helpful. The goal was to improve how families discuss …

This study looked at whether practicing mindfulness can reduce chronic stress and lower colon cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods. Twenty-four women who had a past colon polyp and reported high stress took part. The goal was …