University Of Illinois At Chicago

This study tests whether combining a small surgery to remove blood clots from the brain with a drug called deferoxamine can help people recover better after a brain bleed. About 240 adults aged 18 to 80 with moderate to severe bleeding will be randomly assigned to get the combo t…

This study tests whether empagliflozin, a drug already approved for kidney disease, can slow kidney damage in people with sickle cell anemia. About 20 adults with sickle cell disease and early signs of kidney trouble will take the drug for several months. Researchers will measure…

This study tests whether providing healthy food and cooking lessons can help adults with high blood pressure and obesity lower their blood pressure and weight. About 150 adults will either receive the food and lessons or continue their usual care for 24 weeks. The goal is to see …

This study tests a new program that combines thinking exercises with physical movements to help older adults with mild memory problems. The goal is to improve balance, activity levels, and quality of life, and possibly slow or prevent progression to dementia. 46 people aged 55-90…

This study looks at whether a 12-week high-velocity resistance training program can improve blood flow in the brain and thinking skills in adults aged 60 to 79 who are at higher risk for Alzheimer's disease. Participants will be randomly assigned to either the exercise program or…

This study tests a program called ROCKS that helps people with advanced cancer and their family caregivers have important conversations about future medical care. The goal is to see if the program helps them complete advance directives, feel more resilient, and cope better with a…

This study tests whether clemastine, a common antihistamine, can improve brain health and make antidepressants work better in older adults with depression. About 80 people over age 60 with major depression will receive either clemastine or a placebo alongside their antidepressant…

This study will test whether a 16-week Pilates program done at home via video calls can improve walking, balance, fatigue, and pain in people with multiple sclerosis (MS). About 50 adults with mild to moderate MS will be assigned to either the Pilates group or a waitlist. Researc…

This study tests a 16-week home exercise program for 50 people with Parkinson's disease who are not very active. Participants will either do aerobic and resistance training or simple stretching, all guided by a coach via video calls. The goal is to see if the program increases da…

This study tests a new program where nurses and trained peers help women in Tajikistan who are thinking about suicide. The program is adapted from an existing model and will be tested with 96 women over 9 months. The goal is to reduce suicidal thoughts and actions and see if the …

This study tests a program called On Track for Wellness that uses Fitbit trackers, health education, and goal setting to help people recently diagnosed with psychosis become more active and improve their sleep. About 365 people from Illinois early psychosis programs will take par…

This study looks at whether community health workers (CHWs) can effectively deliver a mental health program to Spanish-speaking Latine parents who have depression, anxiety, or traumatic stress. About 52 parents will either get the program right away or after a 5-month wait. Resea…

This study looks at whether a 6-week program that combines problem-solving therapy with small rewards can help new mothers feel less depressed and drink less alcohol. About 30 mothers who gave birth in the last year will take part. Half will get the program and half will not, and…

This study will develop and test a digital mental health program called 'VIBE in the Parks' for teens and young adults (ages 13-24) who visit Chicago Park District programs. About 268 participants will either use the digital program or receive a digital workbook. The goal is to s…

This study will have about 12 endodontists (dental specialists) wear an Apple Watch during routine root canal treatments to track their heart rate changes. A researcher will note when different steps of the procedure happen to see which parts are most stressful. The goal is to be…

This study will have 10 dental students wear an Apple Watch during routine care to track their heart rate and stress levels. Researchers want to see if treating special-needs patients causes more stress than treating others. The goal is to better understand stress in dental train…

This study looks at how tiny particles from cooking (like frying and grilling) affect memory and breathing in the short term. Fifteen healthy adults will spend two 6-hour sessions in a special room—one with clean air and one with cooking fumes. Researchers will measure lung funct…

This study will test a new care system for people with opioid use disorder across a large health network in Chicago. Researchers want to see if the system increases screening, helps patients stay in care, boosts use of medication, and reduces opioid-related deaths. Over 270,000 p…

This study tests a communication tool designed to help dentists talk with Black men about oral and throat cancers. Researchers will ask 50 Black men to fill out surveys before and after an oral cancer screening with a dentist. The goal is to see if the tool improves understanding…

This study aims to find out how much audio delay people can tolerate when using wireless remote microphones, like those in smartphones. Researchers will test 60 adults with normal hearing and no speech disorders. Participants will rate how annoying different delays feel, helping …

This study looks at how mood, behavior, and brain activity change in young adults (ages 18-21) who use cannabis. Researchers will use brain scans and questionnaires to understand why some people react differently to recreational drugs. The goal is to learn more about substance us…

This pilot study tests whether a program of education, motivation, and social support can help adults with diabetes and early-stage chronic kidney disease (CKD) keep their kidneys healthier. Researchers will enroll 50 people and compare those who receive the program to those who …

This study tests a new program to help families of children with feeding tubes (like G-tubes or NG-tubes) leave the hospital more prepared. About 20 children and their caregivers will either get the special discharge program or usual care. The goal is to see if better education a…