University Of Illinois At Chicago

This study tests whether the drug elranatamab can help keep plasmablastic lymphoma, a rare and aggressive blood cancer, from returning after initial chemotherapy. About 17 adults with or without HIV who have already responded to first treatment will receive elranatamab injections…

This study tests a program called On Track for Wellness, which combines Fitbit activity trackers with health education and goal setting. The goal is to help 365 people recently diagnosed with psychosis improve their sleep and increase physical activity. Researchers want to see if…

This study tests whether a 12-week program of home-delivered DASH-diet groceries and cooking classes can help adults with high blood pressure and obesity lower their blood pressure and lose weight. 150 participants will be randomly assigned to either the food program or usual car…

This study tests whether combining minimally invasive surgery with a drug called deferoxamine helps people recover better after a brain hemorrhage. The surgery removes the blood clot, while the drug may protect brain cells. About 240 adults with moderate to severe bleeding will b…

This study tests whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults aged 60 to 79 who are at higher risk for Alzheimer's disease. Participants will be randomly assigned to either the exercise program or their usu…

This study tests a new cognitive-motor training program for older adults with mild cognitive impairment (MCI), an early stage of dementia. The program combines brain games with balance exercises using computer vision. Researchers want to see if it improves thinking, walking, phys…

This study tests whether a smartphone app called Bodhi AIM can help youth aged 13–20 who are on probation or in related legal programs improve their psychological wellbeing and reduce distress. Participants use the app for one month, following daily guided meditations. The trial …

This study tests two non-invasive treatments—ischemic conditioning (using a blood pressure cuff to briefly restrict blood flow) and neuromuscular electrical stimulation (mild electrical pulses to trigger muscle contractions)—in 24 adults with above- or below-knee amputation. Part…

This study tests whether a low dose of olanzapine, a drug often used for nausea, can help gastric cancer patients avoid weight loss and keep their appetite during chemotherapy before surgery. About 26 adults with stomach cancer will be randomly assigned to receive olanzapine or s…

This study looks at whether adding the drug bupropion (Wellbutrin) to standard hormone therapy can help women with early-stage breast cancer who have lost interest in sex. About 100 women will be randomly assigned to receive either their usual hormone therapy alone or with buprop…

This study tests a 16-week home-based exercise program for people with Parkinson's disease. Fifty participants will either do aerobic and resistance training or just stretching. The goal is to see if the program increases daily physical activity, improves thinking, and enhances q…

This study looks at whether a 6-week program that combines problem-solving therapy with small rewards can help new mothers feel less depressed and drink less alcohol. About 30 mothers who gave birth in the last year will take part. Half will get the program, and the other half wi…

This study will develop and test a digital mental health program called 'VIBE in the Parks' for teens aged 13-24 who use Chicago Park District programs. About 268 participants will either get access to this program or a digital CBT workbook. The goal is to see if the program help…

This study will test whether doing Pilates exercises at home via video calls for 16 weeks can help people with multiple sclerosis (MS) walk farther and faster, improve balance, reduce fatigue and pain, and boost mood and thinking. About 50 adults with mild to moderate MS who can …

This study looks at whether community health workers (CHWs) can effectively provide a mental health program to Spanish-speaking Latine parents who have symptoms of depression, anxiety, or traumatic stress. About 52 parents will either get the program right away or after a 5-month…

This study will test custom smartphone apps and thinking tests to see if they can accurately measure when a patient is ready to leave the hospital alone after anesthesia. Researchers will enroll 1,000 adults having surgery and compare their test results before and after the proce…

This study aims to find out how much audio delay people can tolerate when using wireless remote microphones. Researchers will add artificial delays to sounds played through headphones and ask 60 participants to rate how annoying the delay feels. The goal is to help engineers buil…

This study tests a new care system for people with opioid use disorder across the University of Illinois Hospital and Clinics. Researchers want to see if it increases screening, helps patients stay in care, boosts use of addiction medications, and reduces opioid-related deaths. O…

This study will have about 12 endodontists (dental specialists) wear an Apple Watch during routine root canal procedures to track their heart rate changes. A researcher will note the different stages of treatment to see which parts are most stressful. The goal is to better unders…

This study tests a new education program for parents of children who just got a feeding tube (like a G-tube or NG-tube). The program teaches parents how to care for the tube, get supplies, and handle problems. Researchers want to see if this helps parents feel more confident and …

This study will have 10 dental students wear Apple Watches to monitor their heart rate while treating both special-needs and non-special-needs patients. Researchers want to see if stress levels differ between the two types of care. The goal is to better understand occupational st…

This study will test whether tiny particles released during cooking (like frying and grilling) can temporarily affect memory and lung function. Fifteen healthy adults will spend two separate 6-hour sessions in a special room: one with clean air and one with typical cooking fumes.…

This study tests a culturally tailored communication tool to help dentists discuss oral and pharyngeal cancers with Black men. Researchers will train dental providers and then pilot the tool in community settings with 50 Black men. The goal is to see if the tool improves comfort,…

This pilot study tests a program that provides education, motivation, and social support to adults with diabetes and early-stage chronic kidney disease (CKD). The goal is to see if the program is practical and helps patients stay motivated, learn about kidney disease, and use sup…

This early-phase study will give 144 healthy young adults (ages 18-21) a single dose of THC (7.5 mg) or a placebo in a capsule, then use brain scans and behavioral tasks to measure how THC affects mood, reward processing, and learning. The goal is to understand why some people re…