University Of Illinois At Chicago

This small pilot study is testing whether curcumin, the active ingredient in turmeric, can improve blood vessel health and thinking skills in kidney transplant recipients. Fourteen participants will take either curcumin or a placebo for 12 months. The goal is to see if this safe,…

This study tests a video-based healthy lifestyle program for adults aged 50 to 74 who are overweight and have conditions like prediabetes, type 2 diabetes, or high blood pressure. Participants use a tablet, scale, and activity tracker at home, and some get extra support from a co…

This study tests whether sending different types of messages through a patient portal can encourage smokers to connect with a free quitline coach. About 3000 adult smokers at a health center will receive either a choice-based message, a direct quit message, or just information. T…

This phase II trial tests whether adding targeted total marrow irradiation to standard chemotherapy before a stem cell transplant can help prevent relapse in people with high-risk acute myeloid leukemia or myelodysplastic syndromes. About 38 adults aged 18–65 will receive the com…

This study tests a self-guided online program called CATCH-IT, designed to prevent depression in teenagers who are at risk. Researchers are working with 400 teens aged 13-18 across four health systems to find the best way to deliver this program in primary care. The goal is to se…

This study tests two different programs designed to prevent depression in teenagers who are at risk. One program is an online course called CATCH-IT, and the other is an 8-session group program called TEAMS. About 636 teens aged 13-19 with mild depressive symptoms but no current …

This study tests a suicide prevention program called SUSTAIN, led by nurses and peers, for women at moderate to high suicide risk in Tajikistan. 96 women will be randomly assigned to either the SUSTAIN program or enhanced usual care, and followed for 9 months. The program include…

This study compares time-restricted eating (eating only between 12pm-8pm) to daily calorie restriction for weight loss and colorectal cancer risk reduction in 193 obese adults aged 45-70. Participants follow their assigned diet for 6 months, then a maintenance phase for another 6…

This early-stage study tests a group healthcare model called Centering PrEP+ (C-PrEP+) to help sex workers take and stick with PrEP, a daily pill that prevents HIV. Instead of one-on-one visits, small groups meet with providers for health checks and interactive learning. The stud…

This study tests whether a smartphone app called AIM+ can help juvenile justice officers and other professionals who work with youth in the legal system manage chronic stress, anxiety, and burnout. Over 30 days, participants use the app for short guided meditations and videos. Th…

This study tests whether a guided internet-based physical activity program can improve cognitive processing speed in people with multiple sclerosis. 280 participants who have mild walking difficulties and slowed thinking will be randomly assigned to either the exercise program or…

This study tests whether adding a gentle brain stimulation technique called tDCS to personalized physical therapy can reduce pain and improve function in people with chronic knee pain. Thirty adults with knee pain lasting over 3 months will receive either real or fake tDCS alongs…

This study tests a multi-family therapy program for teens aged 11–18 with anorexia nervosa and their families. The therapy brings several families together to share support and learn skills for meal support and emotional regulation. Researchers will track weight, eating disorder …

This study tests whether a 16-week remote physical activity program can help people recently diagnosed with multiple sclerosis (within 2 years) become more active and improve symptoms like fatigue, depression, and anxiety. Participants receive electronic newsletters, Zoom coachin…

This study looks at whether adding AI-powered images to the surgeon's screen during single-port robotic surgery makes the surgeon's job easier or harder. About 90 urology surgeons and residents will fill out a questionnaire after surgery to rate their mental workload. The goal is…

This study tests a program called 'Enhancing Your Immune Health' for adults with serious mental illness. The program teaches about immune health and how to manage it. Researchers will see if participants report better immune status and feel more confident managing their health.

This study tests a program called Preschool and Me (PreM) that helps families of children with developmental delays or disabilities connect with school-based services. The program uses a care plan and a navigator to guide families through the process. Researchers hope this will i…

This study tests a program called We Walk Plus, which uses a Fitbit activity tracker, personalized text messages, and a private social network to encourage walking in 46 adults aged 35-60 with mild or moderate intellectual disabilities. The goal is to see if the program is feasib…

This study was designed to see if GLP-1 agonists (a type of diabetes medication) change how stiff arteries become after exercise in people with type 2 diabetes. Researchers planned to measure artery stiffness and blood pressure during a cycling test. However, the study was withdr…

This study looks at why depression often comes back in older adults and how it affects memory and thinking. Researchers will follow 210 people aged 60 and older, some currently depressed and some in remission, using brain scans and daily mood tracking. The goal is to find biologi…