Simple home treatments may boost leg strength after amputation
NCT ID NCT07664995
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests two non-invasive treatments—ischemic conditioning (using a blood pressure cuff to briefly restrict blood flow) and neuromuscular electrical stimulation (mild electrical pulses to trigger muscle contractions)—in 24 adults with above- or below-knee amputation. Participants will do one or both treatments at home every other day for two weeks. Researchers will measure changes in walking speed, muscle strength, and movement patterns to see if these therapies can improve function and mobility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ischemic conditioning (blood pressure cuff) and neuromuscular electrical stimulation
- What this could lead to
- If it works, this could point toward a simple home-based therapy to improve walking and muscle strength after leg amputation.
- What could go wrong
- This is a very small early trial (24 people) with no placebo group, so results may not apply widely. The interventions are short-term (2 weeks) and may not produce lasting benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BELOW KNEE AMPUTATION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Illinois Chicago
Chicago, Illinois, 60607, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.