Could a simple nerve stimulation device ease phantom limb pain?

NCT ID NCT07448350

Recruiting now Symptom relief Sponsor: Campus Bio-Medico University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether Transcutaneous Electrical Nerve Stimulation (TENS) can reduce phantom limb pain and improve walking in people with a leg amputation. Fifteen adults with above- or below-knee amputations will receive daily TENS sessions for four weeks. Researchers will measure changes in pain perception, balance, and gait.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcutaneous Electrical Nerve Stimulation (TENS)
What this could lead to: If it works, this could offer a non-drug way to ease phantom limb pain and improve walking for people with leg amputations.
What could go wrong: This is a very small, early study with only 15 people, so results may not apply widely. TENS may not reduce pain for everyone.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOWER LIMB AMPUTATION ABOVE KNEE LOWER LIMB AMPUTATION BELOW KNEE

Contacts and locations

Locations

Don Gnocchi Foundation
RECRUITING

Rome, Rome, 00168, Italy

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