New hope for hard-to-treat leukemia? early trial tests drug combo in 6 patients

NCT ID NCT04926285

First seen Mar 24, 2026 · Last updated May 14, 2026 · Updated 6 times

Summary

This early-phase study tested a combination of two drugs (venetoclax and omacetaxine) in 6 adults with acute myeloid leukemia (AML) whose cancer had stopped responding to standard treatments. The main goal was to find a safe dose of omacetaxine when given with venetoclax. Researchers also looked at whether the combination could shrink or control the cancer. Because this is a very small, early-stage trial, the results are not yet conclusive.

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Contacts and locations

Locations

  • University of Illinois Cancer Center

    Chicago, Illinois, 60612, United States

Conditions

Explore the condition pages connected to this study.