Cancer Institute And Hospital, Chinese Academy Of Medical Sciences

This study aims to find out which treatment approach works better for locally advanced cervical cancer. It will compare the current standard treatment (chemotherapy plus radiation) against a newer approach that adds an immunotherapy drug to chemotherapy before surgery. The goal i…

This study is testing a new combination of two drugs, glecirasib and ivonescimab, for people with advanced non-small cell lung cancer who have a specific genetic change called KRAS G12C and have not yet received treatment. The main goals are to find the safest and most effective …

This is the first-ever study in people to test the safety and early effects of an experimental cell therapy called GC511B for a hard-to-treat type of lung cancer. The trial will enroll 55 adults whose small cell lung cancer has come back or stopped responding to standard treatmen…

This is the first time a new cell therapy called NEUK203-13 Injection is being tested in people. The study aims to see if it is safe and can help control tumors in patients with advanced small cell lung cancer or other neuroendocrine tumors that have stopped responding to standar…

This early-stage study is testing a new gene-editing treatment called EDB-102 for people with advanced lung cancer that has spread to the liver and stopped responding to standard drugs. The treatment uses CRISPR technology, delivered directly to the liver, to try to disable a spe…

This study aims to test the safety and effectiveness of several new cancer treatments and technologies for people with advanced rare solid tumors. Researchers will use detailed molecular testing to match 600 participants with specific treatment options, including drugs, cell ther…

This study is testing whether adding a course of radiation therapy to standard chemotherapy before surgery is safe and more effective for shrinking tumors in patients with locally advanced breast cancer. It focuses on two specific, harder-to-treat types of breast cancer where sta…

This study is testing whether combining three different cancer drugs—sintilimab, surufatinib, and temozolomide—can help control advanced neuroendocrine carcinoma that has worsened after initial treatment. It will enroll 32 adults whose cancer cannot be surgically removed or has s…

This study is testing whether adding two new drugs (adebrelimab and SHR-A1811) to standard chemotherapy is more effective than chemo alone for patients with a specific type of early-stage breast cancer before surgery. The main goal is to see if the new combinations lead more pati…

This study is testing whether adding a new two-drug immunotherapy (iparomlimab and tuvonralimab) to standard platinum chemotherapy works better than chemotherapy alone for advanced triple-negative breast cancer that has worsened after one or two prior treatments. It will involve …

This large study aims to determine if some breast cancer patients can safely skip radiation to the chest wall and lymph nodes after surgery. It will compare cancer recurrence and survival rates between patients who receive this radiation and those who do not. The goal is to reduc…

This study compares two types of lung cancer surgery for patients who have already responded well to immunotherapy. It aims to see if a less extensive surgery, which removes less lung tissue, is as effective at controlling cancer as the standard, more extensive surgery. The goal …

This large study aims to improve treatment for HER2-positive breast cancer by personalizing therapy based on each patient's response. Researchers will test whether adjusting treatment intensity—increasing it for some patients while decreasing it for others—can lead to better outc…

This study is testing whether patients can safely skip having a tube placed through their nose into their stomach after minimally invasive pancreatic cancer surgery. Researchers will compare recovery and complication rates between patients who get the tube as usual and those who …

This study is comparing two different drug combinations for people with advanced colorectal cancer that has spread and stopped responding to standard chemotherapy. Researchers want to see if adding fruquintinib to chemotherapy works better or is safer than adding bevacizumab to t…

This study is testing whether taking a drug called darolutamide, with or without standard hormone therapy, before surgery can better control high-risk prostate cancer. It will involve 60 men with aggressive, localized prostate cancer. Doctors will see if this pre-surgery treatmen…

This study is testing if adding a new immune-boosting drug (Aitua) to standard chemotherapy helps patients with advanced ovarian cancer. The goal is to shrink tumors better before surgery, allowing surgeons to remove all visible cancer. About 82 patients will be randomly assigned…

This study is for women whose advanced cervical cancer has gotten worse after treatment with a common type of immunotherapy (PD-1/PD-L1 drugs). Researchers want to see if a new combination of two immunotherapy drugs plus chemotherapy, with or without an anti-blood-vessel drug, ca…

This early-stage study is testing a new drug called MTM-H-001 for adults with B-cell blood cancers that have returned or stopped responding to standard treatments. The main goal is to find a safe dose and see how the body handles the drug, while also checking for early signs that…

This early-stage study is testing a new, personalized cell therapy called CAT-101 for people with advanced solid tumors that have specific KRAS gene mutations. The therapy involves taking a patient's own immune cells, training them to target the cancer, and then reinfusing them, …

This study is testing a new two-part treatment for aggressive soft tissue cancers in the abdomen (retroperitoneal sarcoma). Doctors want to see if giving a short, intense course of radiation therapy combined with immunotherapy drugs before surgery is safe and feasible. The goal i…

This is an early safety study testing a new type of cell therapy called CAR-Macrophages in patients with advanced solid tumors that have stopped responding to standard treatments. Doctors will collect a patient's own immune cells, genetically engineer them in a lab to recognize a…

This study is testing a new program designed to help patients manage symptoms after surgery for esophageal cancer. The program uses a manual and continuous care procedures to guide recovery. Researchers will compare outcomes between patients who use the program and those who rece…

This study aims to understand how bladder cancer's immune environment changes when patients receive drug treatments before surgery. Researchers will follow 30 patients with muscle-invasive bladder cancer to identify biological markers that might predict which treatments work best…

This study aims to create a detailed map of how colon and rectal cancer spreads to nearby lymph nodes. Researchers will follow 1,200 patients who have had surgery for at least 5 years to see where cancer cells travel. The goal is to use this pattern information to help guide futu…

This study aims to understand why kidney cancer tumors can have different regions, or 'nodules,' and how these differences might lead to drug resistance. Researchers will analyze tumor samples from 10 patients using advanced lab techniques to create detailed genetic maps and test…

This study is testing a new AI chatbot called BaiXiaoAi to see how well it helps cancer patients. The AI will join a private WeChat group with a patient, their doctor, and a nurse to answer questions and share health information. Researchers want to know if the AI's advice is acc…