Personalized combo therapy aims to overcome drug resistance in kidney cancer
NCT ID NCT07630363
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether adding the cholesterol drug atorvastatin to standard targeted therapy (axitinib) and immunotherapy (toripalimab) can help people with advanced kidney cancer who are not responding well to treatment. The drug combination is guided by lab tests on patient-derived tumor cells to identify who might benefit. The trial will enroll 40 participants and focus on safety and tumor shrinkage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- atorvastatin, axitinib, toripalimab
- What this could lead to
- If successful, this could offer a new, personalized treatment option for people with advanced kidney cancer that doesn't respond well to standard therapy.
- What could go wrong
- This is an early-phase trial with only 40 participants, so results may not apply to everyone. The combination may cause side effects or fail to improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing 101205
Beijing, Chaoyang District, 100021, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Cell therapy combo aims to boost kidney cancer treatment
- New drug duo aims to shrink advanced kidney tumors
- Gene test may guide kidney cancer therapy choice
- New kidney cancer drug shows promise in early trial
- New hope for advanced kidney cancer: Triple-Drug combo shows promise
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