Gene test could guide kidney cancer therapy, new trial aims to prove it
NCT ID NCT05361720
First seen Jun 02, 2026 · Last updated Jun 16, 2026 · Updated 2 times
Summary
This study tests whether analyzing the DNA of a kidney tumor can help doctors pick the most effective treatment for advanced or metastatic clear cell renal cell carcinoma. About 54 adults who have not had prior systemic therapy will receive one of two standard drug combinations: two immunotherapies (nivolumab plus ipilimumab) or one immunotherapy plus a targeted pill (nivolumab plus cabozantinib). The goal is to see if genetic matching improves response rates.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chao Family Comprehensive Cancer Center
RECRUITINGOrange, California, 92868, United States
Contact
Contact Email: •••••@•••••
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City of Hope National Medical Center
RECRUITINGDuarte, California, 91010, United States
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Contact Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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University Hospitals Seidman Cancer Center
RECRUITINGCleveland, Ohio, 44106, United States
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Contact Email: •••••@•••••
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University of Texas, Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt University/Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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