Vanderbilt-ingram Cancer Center

This study is testing if adding a drug called neratinib to standard hormone therapy before surgery helps treat a specific type of breast cancer. It is for people with stage I-III lobular breast cancer that has a specific genetic change (HER2 mutation). The goal is to see if this …

This study tests a freezing procedure called cryodevitalization for early-stage lung cancer. During a standard diagnostic lung biopsy, doctors will freeze the tumor to kill cancer cells. The research aims to find the safest and most effective freezing time, and will enroll 30 pat…

This study is testing if a two-step treatment works better for patients with a specific type of digestive system cancer that has spread to the liver. First, surgeons remove as much of the tumor as possible. Then, within 90 days, patients receive a targeted radiation drug that see…

This study is testing a new high-resolution PET-CT scanner designed to help surgeons see cancer margins during surgery. After a tumor is removed, the device scans it in the operating room to check if all cancerous tissue was taken out. The goal is to see if this real-time imaging…

This study is testing a new combined test that uses blood analysis and detailed scan measurements to better determine if a suspicious lung nodule is cancerous or benign. It aims to help doctors decide which patients truly need invasive biopsy procedures. The study will enroll 100…

This study is comparing two different ways to take tissue samples from lung cancer patients during a biopsy procedure. Researchers want to see which method is more likely to collect enough good-quality tissue for advanced genetic testing. The genetic testing helps doctors choose …

This early-stage study is testing a new radioactive imaging drug to see if it can safely and accurately find the first lymph nodes where head and neck cancer has spread. The test involves injecting the drug before surgery and using a special scan to create a map for surgeons. The…

This early-stage study is testing the safety of two new imaging dyes designed to help surgeons see head and neck cancer cells more clearly. The dyes are injected before surgery and make cancer cells glow or show up on special scans, potentially helping surgeons remove more of the…

This study aims to collect and analyze leftover tissue samples from melanoma patients to better understand the biological changes that occur in this type of skin cancer. Researchers will store these samples and study their molecular makeup. The goal is to use this information to …

This study aims to understand the long-term health, vision, and quality of life of children treated for retinoblastoma, a rare eye cancer. Researchers will collect health information, vision tests, saliva samples, and questionnaires from about 900 patients and their siblings over…

This study collects leftover lung tissue from 4,000 patients undergoing surgery for early-stage lung cancer. Researchers analyze these samples to look for specific molecular patterns (like protein and RNA 'fingerprints'). The goal is to learn how these patterns relate to how the …

This study aims to learn how a sarcoma diagnosis and its treatments affect people's health and quality of life over many years. It will follow 2,100 survivors of all ages, collecting health data, activity information from wearable devices, and survey answers. The goal is to ident…

This study is collecting tissue, blood, and urine samples from people with and without breast cancer to create a large repository for research. The goal is to help scientists better understand how breast cancer develops and progresses by studying these samples. Participants' heal…

This study is creating a large registry of people interested in research on inherited cancer risk. It aims to gather health information from up to 10,000 adults to help scientists better understand how genetics influence cancer. Participants complete surveys and may be invited to…

This early study is testing a new approach to help surgeons see head and neck cancer cells during an operation. Researchers are combining an approved cancer drug with a special fluorescent dye. The goal is to see if this combination makes cancer cells glow under a special camera,…